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BET Inhibitors Suppress ALDH Activity by Targeting ALDH1A1 Super-Enhancer in Ovarian Cancer.
Yokoyama Y, Zhu H, Lee JH, Kossenkov AV, Wu SY, Wickramasinghe JM, Yin X, Palozola KC, Gardini A, Showe LC, Zaret KS, Liu Q, Speicher D, Conejo-Garcia JR, Bradner JE, Zhang Z, Sood AK, Ordog T, Bitler BG, Zhang R. Yokoyama Y, et al. Among authors: zhang r, zhang z. Cancer Res. 2016 Nov 1;76(21):6320-6330. doi: 10.1158/0008-5472.CAN-16-0854. Cancer Res. 2016. PMID: 27803105 Free PMC article.
CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.
Karakashev S, Zhu H, Wu S, Yokoyama Y, Bitler BG, Park PH, Lee JH, Kossenkov AV, Gaonkar KS, Yan H, Drapkin R, Conejo-Garcia JR, Speicher DW, Ordog T, Zhang R. Karakashev S, et al. Among authors: zhang r. Nat Commun. 2018 Feb 12;9(1):631. doi: 10.1038/s41467-018-03031-3. Nat Commun. 2018. PMID: 29434212 Free PMC article.
ARID1A promotes genomic stability through protecting telomere cohesion.
Zhao B, Lin J, Rong L, Wu S, Deng Z, Fatkhutdinov N, Zundell J, Fukumoto T, Liu Q, Kossenkov A, Jean S, Cadungog MG, Borowsky ME, Drapkin R, Lieberman PM, Abate-Shen CT, Zhang R. Zhao B, et al. Among authors: zhang r. Nat Commun. 2019 Sep 6;10(1):4067. doi: 10.1038/s41467-019-12037-4. Nat Commun. 2019. PMID: 31492885 Free PMC article.
ARID1A mutation and genomic stability.
Nacarelli T, Zhao B, Hao X, Zhang R. Nacarelli T, et al. Among authors: zhang r. Mol Cell Oncol. 2020 Feb 23;7(3):1690923. doi: 10.1080/23723556.2019.1690923. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32391414 Free PMC article.
Targeting cellular senescence to combat cancer and ageing.
Wang C, Hao X, Zhang R. Wang C, et al. Among authors: zhang r. Mol Oncol. 2022 Sep;16(18):3319-3332. doi: 10.1002/1878-0261.13266. Epub 2022 Jun 20. Mol Oncol. 2022. PMID: 35674055 Free PMC article. Review.
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