Zhang Q - Search Results

1

An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo.

Xing Y, Guo W, Wu M, Xie J, Huang D, Hu P, Zhou M, Zhang L, Zhang Q, Wang P, Wang X, Wang G, Wu H, Zhou C, Chen Y, Liu M, Yi Z, Sun Z. Xing Y, et al. Among authors: zhang l, zhang q. Cancer Lett. 2022 Mar 31;529:100-111. doi: 10.1016/j.canlet.2021.12.035. Epub 2022 Jan 4. Cancer Lett. 2022. PMID: 34990752

2

Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy.

Yang JJ, Yu WW, Hu LL, Liu WJ, Lin XH, Wang W, Zhang Q, Wang PL, Tang SW, Wang X, Liu M, Lu W, Zhang HK. Yang JJ, et al. Among authors: zhang q, zhang hk. J Med Chem. 2020 Jan 23;63(2):569-590. doi: 10.1021/acs.jmedchem.9b01269. Epub 2020 Jan 2. J Med Chem. 2020. PMID: 31855426

3

Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.

Guo W, Xing Y, Zhang Q, Xie J, Huang D, Gu H, He P, Zhou M, Xu S, Pang X, Liu M, Yi Z, Chen Y. Guo W, et al. Among authors: zhang q. J Med Chem. 2020 Jan 23;63(2):676-695. doi: 10.1021/acs.jmedchem.9b01618. Epub 2020 Jan 13. J Med Chem. 2020. PMID: 31895575

4

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis.

Jiang X, Chen S, Zhang Q, Yi C, He J, Ye X, Liu M, Lu W. Jiang X, et al. Among authors: zhang q. Phytomedicine. 2020 Feb;67:153160. doi: 10.1016/j.phymed.2019.153160. Epub 2019 Dec 26. Phytomedicine. 2020. PMID: 31901889

5

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer.

Lu W, Yu W, He J, Liu W, Yang J, Lin X, Zhang Y, Wang X, Jiang W, Luo J, Zhang Q, Yang H, Peng S, Yi Z, Ren S, Chen J, Siwko S, Nussinov R, Cheng F, Zhang H, Liu M. Lu W, et al. Among authors: zhang q, zhang h, zhang y. EMBO Mol Med. 2021 Jan 11;13(1):e12798. doi: 10.15252/emmm.202012798. Epub 2020 Dec 7. EMBO Mol Med. 2021. PMID: 33283987 Free PMC article.

6

Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse.

Li H, Zhang Q, Gu Y, Wu Y, Wang Y, Wang L, Feng S, Hu Y, Zheng Y, Li Y, Ye H, Zhou B, Lin L, Liu M, Yang H, Li D. Li H, et al. Among authors: zhang q. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33426-33435. doi: 10.1073/pnas.2003991117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318209 Free PMC article.

7

From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis.

Jiang BE, Jiang X, Zhang Q, Liang Q, Qiu ZL, Sun XB, Yang JJ, Chen S, Yi C, Chai X, Liu M, Yu LF, Lu W, Zhang HK. Jiang BE, et al. Among authors: zhang q, zhang hk. J Med Chem. 2021 Jan 14;64(1):385-403. doi: 10.1021/acs.jmedchem.0c01023. Epub 2020 Dec 31. J Med Chem. 2021. PMID: 33382613

8

Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy.

Wang W, He J, Yang J, Zhang C, Cheng Z, Zhang Y, Zhang Q, Wang P, Tang S, Wang X, Liu M, Lu W, Zhang HK. Wang W, et al. Among authors: zhang c, zhang q, zhang hk, zhang y. J Med Chem. 2022 Jun 9;65(11):7896-7917. doi: 10.1021/acs.jmedchem.2c00448. Epub 2022 May 31. J Med Chem. 2022. PMID: 35640059

9

Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer.

Chen H, Zhou W, Bian A, Zhang Q, Miao Y, Yin X, Ye J, Xu S, Ti C, Sun Z, Zheng J, Chen Y, Liu M, Yi Z. Chen H, et al. Among authors: zhang q. Clin Cancer Res. 2023 Feb 16;29(4):815-830. doi: 10.1158/1078-0432.CCR-22-0997. Clin Cancer Res. 2023. PMID: 36374556

10

Discovery of 2H-Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy.

Cheng Z, Wang Y, Zhang Y, Zhang C, Wang M, Wang W, He J, Wang Y, Zhang H, Zhang Q, Ding C, Wu D, Yang L, Liu M, Lu W. Cheng Z, et al. Among authors: zhang c, zhang q, zhang h, zhang y. J Med Chem. 2023 May 11;66(9):6218-6238. doi: 10.1021/acs.jmedchem.2c02058. Epub 2023 Mar 7. J Med Chem. 2023. PMID: 36880691

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