Zhang N - Search Results

1

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, Ni T, Zhang ZS, Zhang T, Li C, Han L, Zhu Z, Lian F, Wei J, Deng Q, Wang Y, Wunderlich M, Gao Z, Pan G, Zhong D, Zhou H, Zhang N, Gan J, Jiang H, Mulloy JC, Qian Z, Chen J, Yang CG. Huang Y, et al. Among authors: zhang n, zhang zs, zhang t. Cancer Cell. 2019 Apr 15;35(4):677-691.e10. doi: 10.1016/j.ccell.2019.03.006. Cancer Cell. 2019. PMID: 30991027 Free PMC article.

2

Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1).

Xie Y, Zhou R, Lian F, Liu Y, Chen L, Shi Z, Zhang N, Zheng M, Shen B, Jiang H, Liang Z, Luo C. Xie Y, et al. Among authors: zhang n. Org Biomol Chem. 2014 Dec 21;12(47):9665-73. doi: 10.1039/c4ob01591f. Epub 2014 Oct 28. Org Biomol Chem. 2014. PMID: 25348815

3

Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.

Kong X, Chen L, Jiao L, Jiang X, Lian F, Lu J, Zhu K, Du D, Liu J, Ding H, Zhang N, Shen J, Zheng M, Chen K, Liu X, Jiang H, Luo C. Kong X, et al. Among authors: zhang n. J Med Chem. 2014 Nov 26;57(22):9512-21. doi: 10.1021/jm501230c. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25369470

4

Two-quartet G-quadruplexes formed by DNA sequences containing four contiguous GG runs.

Qin M, Chen Z, Luo Q, Wen Y, Zhang N, Jiang H, Yang H. Qin M, et al. Among authors: zhang n. J Phys Chem B. 2015 Mar 5;119(9):3706-13. doi: 10.1021/jp512914t. Epub 2015 Feb 24. J Phys Chem B. 2015. PMID: 25689673

5

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.

Wang J, Luo C, Shan C, You Q, Lu J, Elf S, Zhou Y, Wen Y, Vinkenborg JL, Fan J, Kang H, Lin R, Han D, Xie Y, Karpus J, Chen S, Ouyang S, Luan C, Zhang N, Ding H, Merkx M, Liu H, Chen J, Jiang H, He C. Wang J, et al. Among authors: zhang n. Nat Chem. 2015 Dec;7(12):968-79. doi: 10.1038/nchem.2381. Epub 2015 Nov 9. Nat Chem. 2015. PMID: 26587712 Free PMC article.

6

Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence.

Chen F, Di H, Wang Y, Cao Q, Xu B, Zhang X, Yang N, Liu G, Yang CG, Xu Y, Jiang H, Lian F, Zhang N, Li J, Lan L. Chen F, et al. Among authors: zhang n, zhang x. Nat Chem Biol. 2016 Mar;12(3):174-9. doi: 10.1038/nchembio.2003. Epub 2016 Jan 18. Nat Chem Biol. 2016. PMID: 26780405

7

NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds.

Yu JL, Chen TT, Zhou C, Lian FL, Tang XL, Wen Y, Shen JK, Xu YC, Xiong B, Zhang NX. Yu JL, et al. Acta Pharmacol Sin. 2016 Jul;37(7):984-93. doi: 10.1038/aps.2016.19. Epub 2016 May 30. Acta Pharmacol Sin. 2016. PMID: 27238211 Free PMC article.

8

Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide.

Yue L, Du J, Ye F, Chen Z, Li L, Lian F, Zhang B, Zhang Y, Jiang H, Chen K, Li Y, Zhou B, Zhang N, Yang Y, Luo C. Yue L, et al. Among authors: zhang n, zhang b, zhang y. Org Biomol Chem. 2016 Sep 28;14(36):8503-19. doi: 10.1039/c6ob01248e. Epub 2016 Aug 19. Org Biomol Chem. 2016. PMID: 27541268

9

Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents.

Li X, Wang H, Lu Z, Zheng X, Ni W, Zhu J, Fu Y, Lian F, Zhang N, Li J, Zhang H, Mao F. Li X, et al. Among authors: zhang n, zhang h. J Med Chem. 2016 Sep 22;59(18):8326-44. doi: 10.1021/acs.jmedchem.6b00636. Epub 2016 Sep 6. J Med Chem. 2016. PMID: 27552582

10

Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer.

Guo ZQ, Zheng T, Chen B, Luo C, Ouyang S, Gong S, Li J, Mao LL, Lian F, Yang Y, Huang Y, Li L, Lu J, Zhang B, Zhou L, Ding H, Gao Z, Zhou L, Li G, Zhou R, Chen K, Liu J, Wen Y, Gong L, Ke Y, Yang SD, Qiu XB, Zhang N, Ren J, Zhong D, Yang CG, Liu J, Jiang H. Guo ZQ, et al. Among authors: zhang n, zhang b. Cancer Cell. 2016 Sep 12;30(3):474-484. doi: 10.1016/j.ccell.2016.08.003. Cancer Cell. 2016. PMID: 27622336 Free article.

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