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The E3 ubiquitin ligase TRIM31 plays a critical role in hypertensive nephropathy by promoting proteasomal degradation of MAP3K7 in the TGF-β1 signaling pathway.
Zhang J, Cao L, Wang X, Li Q, Zhang M, Cheng C, Yu L, Xue F, Sui W, Sun S, Li N, Bu P, Liu B, Gao F, Zhen J, Su G, Zhang C, Gao C, Zhang M, Zhang Y. Zhang J, et al. Among authors: zhang m, zhang c, zhang y. Cell Death Differ. 2022 Mar;29(3):556-567. doi: 10.1038/s41418-021-00874-0. Epub 2021 Sep 28. Cell Death Differ. 2022. PMID: 34584221 Free PMC article.
An intersegmental single-cell profile reveals aortic heterogeneity and identifies a novel Malat1+ vascular smooth muscle subtype involved in abdominal aortic aneurysm formation.
Yu L, Zhang J, Gao A, Zhang M, Wang Z, Yu F, Guo X, Su G, Zhang Y, Zhang M, Zhang C. Yu L, et al. Among authors: zhang m, zhang c, zhang j, zhang y. Signal Transduct Target Ther. 2022 Apr 27;7(1):125. doi: 10.1038/s41392-022-00943-x. Signal Transduct Target Ther. 2022. PMID: 35473929 Free PMC article.
ADAM17 knockdown mitigates while ADAM17 overexpression aggravates cardiac fibrosis and dysfunction via regulating ACE2 shedding and myofibroblast transformation.
Cheng J, Xue F, Cheng C, Sui W, Zhang M, Qiao L, Ma J, Ji X, Chen W, Yu X, Xi B, Xu F, Su G, Zhao Y, Hao P, Zhang Y, Zhang C. Cheng J, et al. Among authors: zhang m, zhang c, zhang y. Front Pharmacol. 2022 Oct 14;13:997916. doi: 10.3389/fphar.2022.997916. eCollection 2022. Front Pharmacol. 2022. PMID: 36313337 Free PMC article.
METTL3 (Methyltransferase Like 3)-Dependent N6-Methyladenosine Modification on Braf mRNA Promotes Macrophage Inflammatory Response and Atherosclerosis in Mice.
Li Q, Yu L, Gao A, Ren R, Zhang J, Cao L, Wang X, Liu Y, Qi W, Cai L, Li W, Wang W, Guo X, Su G, Yu X, Zhang J, Xi B, Zhang Y, Zhang M, Zhang C. Li Q, et al. Among authors: zhang m, zhang c, zhang j, zhang y. Arterioscler Thromb Vasc Biol. 2023 May;43(5):755-773. doi: 10.1161/ATVBAHA.122.318451. Epub 2023 Mar 23. Arterioscler Thromb Vasc Biol. 2023. PMID: 36951060
LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles.
Qiao L, Hu J, Qiu X, Wang C, Peng J, Zhang C, Zhang M, Lu H, Chen W. Qiao L, et al. Among authors: zhang m, zhang c. Autophagy. 2023 Nov;19(11):2837-2852. doi: 10.1080/15548627.2023.2235196. Epub 2023 Jul 21. Autophagy. 2023. PMID: 37469132 Free PMC article. Review.
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