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Allosteric activation of MALT1 by its ubiquitin-binding Ig3 domain.
Schairer R, Hall G, Zhang M, Cowan R, Baravalle R, Muskett FW, Coombs PJ, Mpamhanga C, Hale LR, Saxty B, Iwaszkiewicz J, Décaillet C, Perroud M, Carr MD, Thome M. Schairer R, et al. Among authors: zhang m. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3093-3102. doi: 10.1073/pnas.1912681117. Epub 2020 Jan 24. Proc Natl Acad Sci U S A. 2020. PMID: 31980531 Free PMC article.
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.
Cheng J, Klei LR, Hubel NE, Zhang M, Schairer R, Maurer LM, Klei HB, Kang H, Concel VJ, Delekta PC, Dang EV, Mintz MA, Baens M, Cyster JG, Parameswaran N, Thome M, Lucas PC, McAllister-Lucas LM. Cheng J, et al. Among authors: zhang m. J Clin Invest. 2020 Feb 3;130(2):1036-1051. doi: 10.1172/JCI97040. J Clin Invest. 2020. PMID: 31961340 Free PMC article.
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