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GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner.
Jiang SH, Zhu LL, Zhang M, Li RK, Yang Q, Yan JY, Zhang C, Yang JY, Dong FY, Dai M, Hu LP, Li J, Li Q, Wang YH, Yang XM, Zhang YL, Nie HZ, Zhu L, Zhang XL, Tian GA, Zhang XX, Cao XY, Tao LY, Huang S, Jiang YS, Hua R, Qian Luo K, Gu JR, Sun YW, Hou S, Zhang ZG. Jiang SH, et al. Among authors: zhang xl, zhang m, zhang c, zhang zg, zhang yl, zhang xx. Gut. 2019 Nov;68(11):1994-2006. doi: 10.1136/gutjnl-2018-317479. Epub 2019 Mar 2. Gut. 2019. PMID: 30826748
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.
Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y, Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H, Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH. Cheng C, et al. Among authors: zhang m, zhang p, zhang j, zhang k. Nat Cancer. 2022 May;3(5):565-580. doi: 10.1038/s43018-022-00380-3. Epub 2022 May 27. Nat Cancer. 2022. PMID: 35624341
Hippo cooperates with p53 to maintain foregut homeostasis and suppress the malignant transformation of foregut basal progenitor cells.
Jiang Y, Huang H, Liu J, Luo D, Mu R, Yuan J, Lin J, Chen Q, Tao W, Yang L, Zhang M, Zhang P, Fang F, Xu J, Gong Q, Xie Z, Zhang Y. Jiang Y, et al. Among authors: zhang m, zhang p, zhang y. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2320559121. doi: 10.1073/pnas.2320559121. Epub 2024 Feb 26. Proc Natl Acad Sci U S A. 2024. PMID: 38408237
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