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SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.
Zhang L, Kempf A, Nehlmeier I, Cossmann A, Richter A, Bdeir N, Graichen L, Moldenhauer AS, Dopfer-Jablonka A, Stankov MV, Simon-Loriere E, Schulz SR, Jäck HM, Čičin-Šain L, Behrens GMN, Drosten C, Hoffmann M, Pöhlmann S. Zhang L, et al. Cell. 2024 Feb 1;187(3):596-608.e17. doi: 10.1016/j.cell.2023.12.025. Epub 2024 Jan 8. Cell. 2024. PMID: 38194966
SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization.
Hoffmann M, Zhang L, Krüger N, Graichen L, Kleine-Weber H, Hofmann-Winkler H, Kempf A, Nessler S, Riggert J, Winkler MS, Schulz S, Jäck HM, Pöhlmann S. Hoffmann M, et al. Among authors: zhang l. Cell Rep. 2021 Apr 20;35(3):109017. doi: 10.1016/j.celrep.2021.109017. Epub 2021 Apr 3. Cell Rep. 2021. PMID: 33857422 Free PMC article.
SARS-CoV-2 Omicron sublineages show comparable cell entry but differential neutralization by therapeutic antibodies.
Arora P, Zhang L, Krüger N, Rocha C, Sidarovich A, Schulz S, Kempf A, Graichen L, Moldenhauer AS, Cossmann A, Dopfer-Jablonka A, Behrens GMN, Jäck HM, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: zhang l. Cell Host Microbe. 2022 Aug 10;30(8):1103-1111.e6. doi: 10.1016/j.chom.2022.04.017. Epub 2022 May 6. Cell Host Microbe. 2022. PMID: 35588741 Free PMC article.
Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3.
Arora P, Zhang L, Rocha C, Sidarovich A, Kempf A, Schulz S, Cossmann A, Manger B, Baier E, Tampe B, Moerer O, Dickel S, Dopfer-Jablonka A, Jäck HM, Behrens GMN, Winkler MS, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: zhang l. Lancet Infect Dis. 2022 Jun;22(6):766-767. doi: 10.1016/S1473-3099(22)00224-9. Epub 2022 Apr 12. Lancet Infect Dis. 2022. PMID: 35427493 Free PMC article. No abstract available.
The SARS-CoV-2 Delta-Omicron Recombinant Lineage (XD) Exhibits Immune-Escape Properties Similar to the Omicron (BA.1) Variant.
Arora P, Zhang L, Rocha C, Graichen L, Nehlmeier I, Kempf A, Cossmann A, Ramos GM, Baier E, Tampe B, Moerer O, Dickel S, Winkler MS, Behrens GMN, Pöhlmann S, Hoffmann M. Arora P, et al. Among authors: zhang l. Int J Mol Sci. 2022 Nov 14;23(22):14057. doi: 10.3390/ijms232214057. Int J Mol Sci. 2022. PMID: 36430535 Free PMC article.
Omicron subvariant BA.5 efficiently infects lung cells.
Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Hoffmann M, et al. Among authors: zhang l. Nat Commun. 2023 Jun 13;14(1):3500. doi: 10.1038/s41467-023-39147-4. Nat Commun. 2023. PMID: 37311762 Free PMC article.
Neutralisation sensitivity of SARS-CoV-2 lineages EG.5.1 and XBB.2.3.
Zhang L, Kempf A, Nehlmeier I, Cossmann A, Dopfer-Jablonka A, Stankov MV, Schulz SR, Jäck HM, Behrens GMN, Pöhlmann S, Hoffmann M. Zhang L, et al. Lancet Infect Dis. 2023 Oct;23(10):e391-e392. doi: 10.1016/S1473-3099(23)00547-9. Epub 2023 Sep 13. Lancet Infect Dis. 2023. PMID: 37716358 No abstract available.
Omicron: Master of immune evasion maintains robust ACE2 binding.
Hoffmann M, Zhang L, Pöhlmann S. Hoffmann M, et al. Among authors: zhang l. Signal Transduct Target Ther. 2022 Apr 7;7(1):118. doi: 10.1038/s41392-022-00965-5. Signal Transduct Target Ther. 2022. PMID: 35393393 Free PMC article. No abstract available.
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