Zhang L - Search Results

1

Mitochondrial fatty acid oxidation is the major source of cardiac adenosine triphosphate production in heart failure with preserved ejection fraction.

Sun Q, Güven B, Wagg CS, Almeida de Oliveira A, Silver H, Zhang L, Chen B, Wei K, Ketema EB, Karwi QG, Persad KL, Vu J, Wang F, Dyck JRB, Oudit GY, Lopaschuk GD. Sun Q, et al. Among authors: zhang l. Cardiovasc Res. 2024 Mar 30;120(4):360-371. doi: 10.1093/cvr/cvae006. Cardiovasc Res. 2024. PMID: 38193548

2

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase.

Ussher JR, Koves TR, Jaswal JS, Zhang L, Ilkayeva O, Dyck JR, Muoio DM, Lopaschuk GD. Ussher JR, et al. Among authors: zhang l. Diabetes. 2009 Aug;58(8):1766-75. doi: 10.2337/db09-0011. Epub 2009 May 28. Diabetes. 2009. PMID: 19478144 Free PMC article.

3

Role of fatty acid uptake and fatty acid beta-oxidation in mediating insulin resistance in heart and skeletal muscle.

Zhang L, Keung W, Samokhvalov V, Wang W, Lopaschuk GD. Zhang L, et al. Biochim Biophys Acta. 2010 Jan;1801(1):1-22. doi: 10.1016/j.bbalip.2009.09.014. Epub 2009 Sep 24. Biochim Biophys Acta. 2010. PMID: 19782765 Review.

4

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

Basu R, Oudit GY, Wang X, Zhang L, Ussher JR, Lopaschuk GD, Kassiri Z. Basu R, et al. Among authors: zhang l. Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2096-108. doi: 10.1152/ajpheart.00452.2009. Epub 2009 Oct 2. Am J Physiol Heart Circ Physiol. 2009. PMID: 19801494 Free article.

5

High levels of fatty acids increase contractile function of neonatal rabbit hearts during reperfusion following ischemia.

Ito M, Jaswal JS, Lam VH, Oka T, Zhang L, Beker DL, Lopaschuk GD, Rebeyka IM. Ito M, et al. Among authors: zhang l. Am J Physiol Heart Circ Physiol. 2010 May;298(5):H1426-37. doi: 10.1152/ajpheart.00284.2009. Epub 2010 Feb 12. Am J Physiol Heart Circ Physiol. 2010. PMID: 20154256 Free article.

6

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption.

Ussher JR, Koves TR, Cadete VJ, Zhang L, Jaswal JS, Swyrd SJ, Lopaschuk DG, Proctor SD, Keung W, Muoio DM, Lopaschuk GD. Ussher JR, et al. Among authors: zhang l. Diabetes. 2010 Oct;59(10):2453-64. doi: 10.2337/db09-1293. Epub 2010 Jun 3. Diabetes. 2010. PMID: 20522596 Free PMC article.

7

Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift.

Wang L, Ko KW, Lucchinetti E, Zhang L, Troxler H, Hersberger M, Omar MA, Posse de Chaves EI, Lopaschuk GD, Clanachan AS, Zaugg M. Wang L, et al. Among authors: zhang l. Anesthesiology. 2010 Sep;113(3):541-51. doi: 10.1097/ALN.0b013e3181e2c1a1. Anesthesiology. 2010. PMID: 20683255 Free article.

8

Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation.

Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD. Zhang L, et al. Cardiovasc Res. 2011 Jan 1;89(1):148-56. doi: 10.1093/cvr/cvq266. Epub 2010 Aug 20. Cardiovasc Res. 2011. PMID: 20729341

9

Cardiac hypertrophy in the newborn delays the maturation of fatty acid β-oxidation and compromises postischemic functional recovery.

Oka T, Lam VH, Zhang L, Keung W, Cadete VJ, Samokhvalov V, Tanner BA, Beker DL, Ussher JR, Huqi A, Jaswal JS, Rebeyka IM, Lopaschuk GD. Oka T, et al. Among authors: zhang l. Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1784-94. doi: 10.1152/ajpheart.00804.2011. Epub 2012 Mar 9. Am J Physiol Heart Circ Physiol. 2012. PMID: 22408020 Free article.

10

Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding.

Zhang L, Mori J, Wagg C, Lopaschuk GD. Zhang L, et al. FEBS Lett. 2012 Apr 5;586(7):996-1003. doi: 10.1016/j.febslet.2012.02.027. Epub 2012 Mar 3. FEBS Lett. 2012. PMID: 22569253 Free article.

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