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Viral anti-inflammatory serpin reduces immuno-coagulopathic pathology in SARS-CoV-2 mouse models of infection.
Zhang L, Li YH, Kibler K, Kraberger S, Varsani A, Turk J, Elmadbouly N, Aliskevich E, Spaccarelli L, Estifanos B, Enow J, Zanetti IR, Saldevar N, Lim E, Schlievert J, Browder K, Wilson A, Juan FA, Pinteric A, Garg A, Monder H, Saju R, Gisriel S, Jacobs B, Karr TL, Florsheim EB, Kumar V, Wallen J, Rahman M, McFadden G, Hogue BG, Lucas AR. Zhang L, et al. EMBO Mol Med. 2023 Sep 11;15(9):e17376. doi: 10.15252/emmm.202317376. Epub 2023 Aug 3. EMBO Mol Med. 2023. PMID: 37534622 Free PMC article.
PEGylated Serp-1 Markedly Reduces Pristane-Induced Experimental Diffuse Alveolar Hemorrhage, Altering uPAR Distribution, and Macrophage Invasion.
Guo Q, Yaron JR, Wallen JW 3rd, Browder KF, Boyd R, Olson TL, Burgin M, Ulrich P, Aliskevich E, Schutz LN, Fromme P, Zhang L, Lucas AR. Guo Q, et al. Among authors: zhang l. Front Cardiovasc Med. 2021 Feb 16;8:633212. doi: 10.3389/fcvm.2021.633212. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33665212 Free PMC article.
The under-appreciated world of the serpin family of serine proteinase inhibitors.
Bouton MC, Geiger M, Sheffield WP, Irving JA, Lomas DA, Song S, Satyanarayanan RS, Zhang L, McFadden G, Lucas AR. Bouton MC, et al. Among authors: zhang l. EMBO Mol Med. 2023 Jun 7;15(6):e17144. doi: 10.15252/emmm.202217144. Epub 2023 May 9. EMBO Mol Med. 2023. PMID: 37158379 Free PMC article.
Serpins: Development for Therapeutic Applications.
Lucas A, Yaron JR, Zhang L, Macaulay C, McFadden G. Lucas A, et al. Among authors: zhang l. Methods Mol Biol. 2018;1826:255-265. doi: 10.1007/978-1-4939-8645-3_17. Methods Mol Biol. 2018. PMID: 30194606 Review.
Immune protection is dependent on the gut microbiome in a lethal mouse gammaherpesviral infection.
Yaron JR, Ambadapadi S, Zhang L, Chavan RN, Tibbetts SA, Keinan S, Varsani A, Maldonado J, Kraberger S, Tafoya AM, Bullard WL, Kilbourne J, Stern-Harbutte A, Krajmalnik-Brown R, Munk BH, Koppang EO, Lim ES, Lucas AR. Yaron JR, et al. Among authors: zhang l. Sci Rep. 2020 Feb 11;10(1):2371. doi: 10.1038/s41598-020-59269-9. Sci Rep. 2020. PMID: 32047224 Free PMC article.
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