Zhang L - Search Results

1

Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer.

Zhang Y, Du T, Liu N, Wang J, Zhang L, Cui CP, Li C, Zhang X, Wu B, Zhang J, Jiang W, Zhang Y, Zhang Y, Li H, Li P. Zhang Y, et al. Among authors: zhang l, zhang j, zhang x. Cell Death Dis. 2023 Jun 27;14(6):378. doi: 10.1038/s41419-023-05900-2. Cell Death Dis. 2023. PMID: 37369659 Free PMC article.

2

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

Lu L, Hu S, Wei R, Qiu X, Lu K, Fu Y, Li H, Xing G, Li D, Peng R, He F, Zhang L. Lu L, et al. Among authors: zhang l. J Biol Chem. 2013 Dec 13;288(50):35637-50. doi: 10.1074/jbc.M113.472076. Epub 2013 Oct 25. J Biol Chem. 2013. PMID: 24163370 Free PMC article.

3

Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis.

Yuan L, Lv Y, Li H, Gao H, Song S, Zhang Y, Xing G, Kong X, Wang L, Li Y, Zhou T, Gao D, Xiao ZX, Yin Y, Wei W, He F, Zhang L. Yuan L, et al. Among authors: zhang l, zhang y. Nat Cell Biol. 2015 Sep;17(9):1169-81. doi: 10.1038/ncb3218. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280536

4

KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration.

Wang S, Peng Z, Wang S, Yang L, Chen Y, Kong X, Song S, Pei P, Tian C, Yan H, Ding P, Hu W, Liu CH, Zhang X, He F, Zhang L. Wang S, et al. Among authors: zhang l, zhang x. Cell Res. 2018 May;28(5):572-592. doi: 10.1038/s41422-018-0008-8. Epub 2018 Feb 21. Cell Res. 2018. PMID: 29467382 Free PMC article.

5

Smad ubiquitylation regulatory factor 1 promotes LIM-homeobox gene 9 degradation and represses testosterone production in Leydig cells.

Hu F, Zhu Q, Sun B, Cui C, Li C, Zhang L. Hu F, et al. Among authors: zhang l. FASEB J. 2018 Sep;32(9):4627-4640. doi: 10.1096/fj.201701480R. Epub 2018 Mar 22. FASEB J. 2018. PMID: 29565736

Our results provide new insights into the molecular events that play a role in the homeostasis of testosterone levels and may provide a new target for testosterone regulation.-Hu, F., Zhu, Q., Sun, B., Cui, C., Li, C., Zhang, L. Smad ubiquitylation regulatory factor …

Our results provide new insights into the molecular events that play a role in the homeostasis of testosterone levels and may provide a new …

6

Author Correction: KRAB-type zinc-finger proteins PITA and PISA specifically regulate p53-dependent glycolysis and mitochondrial respiration.

Wang S, Peng Z, Wang S, Yang L, Chen Y, Kong X, Song S, Pei P, Tian C, Yan H, Ding P, Hu W, Liu CH, Zhang X, He F, Zhang L. Wang S, et al. Among authors: zhang l, zhang x. Cell Res. 2018 May;28(5):605. doi: 10.1038/s41422-018-0026-6. Cell Res. 2018. PMID: 29572487 Free PMC article.

7

WWP2 is a physiological ubiquitin ligase for phosphatase and tensin homolog (PTEN) in mice.

Li H, Zhang P, Zhang Q, Li C, Zou W, Chang Z, Cui CP, Zhang L. Li H, et al. Among authors: zhang l, zhang p, zhang q. J Biol Chem. 2018 Jun 8;293(23):8886-8899. doi: 10.1074/jbc.RA117.001060. Epub 2018 Apr 23. J Biol Chem. 2018. PMID: 29685889 Free PMC article.

8

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth.

Chen Y, Huang Q, Liu W, Zhu Q, Cui CP, Xu L, Guo X, Wang P, Liu J, Dong G, Wei W, Liu CH, Feng Z, He F, Zhang L. Chen Y, et al. Among authors: zhang l. Nat Commun. 2018 Jun 25;9(1):2464. doi: 10.1038/s41467-018-04815-3. Nat Commun. 2018. PMID: 29942010 Free PMC article.

9

VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation.

Li H, Cui Y, Wei J, Liu C, Chen Y, Cui CP, Li L, Zhang X, Zhang L. Li H, et al. Among authors: zhang l, zhang x. FASEB J. 2019 Feb;33(2):2928-2943. doi: 10.1096/fj.201801173R. Epub 2018 Oct 18. FASEB J. 2019. PMID: 30335548

-Li, H., Cui, Y., Wei, J., Liu, C., Chen, Y., Cui, C.-P., Li, L., Zhang, X., Zhang, L. VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation....

-Li, H., Cui, Y., Wei, J., Liu, C., Chen, Y., Cui, C.-P., Li, L., Zhang, X., Zhang, L. VCP/p97 increases BMP sig …

10

Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation.

Cui CP, Zhang Y, Wang C, Yuan F, Li H, Yao Y, Chen Y, Li C, Wei W, Liu CH, He F, Liu Y, Zhang L. Cui CP, et al. Among authors: zhang l, zhang y. Nat Commun. 2018 Nov 7;9(1):4648. doi: 10.1038/s41467-018-07025-z. Nat Commun. 2018. PMID: 30405104 Free PMC article.

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