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Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation.
Xu H, Van der Jeught K, Zhou Z, Zhang L, Yu T, Sun Y, Li Y, Wan C, So KM, Liu D, Frieden M, Fang Y, Mosley AL, He X, Zhang X, Sandusky GE, Liu Y, Meroueh SO, Zhang C, Wijeratne AB, Huang C, Ji G, Lu X. Xu H, et al. Among authors: zhang l, zhang c, zhang x. J Clin Invest. 2021 May 17;131(10):e146832. doi: 10.1172/JCI146832. J Clin Invest. 2021. PMID: 33830945 Free PMC article.
An organoid-based screen for epigenetic inhibitors that stimulate antigen presentation and potentiate T-cell-mediated cytotoxicity.
Zhou Z, Van der Jeught K, Fang Y, Yu T, Li Y, Ao Z, Liu S, Zhang L, Yang Y, Eyvani H, Cox ML, Wang X, He X, Ji G, Schneider BP, Guo F, Wan J, Zhang X, Lu X. Zhou Z, et al. Among authors: zhang l, zhang x. Nat Biomed Eng. 2021 Nov;5(11):1320-1335. doi: 10.1038/s41551-021-00805-x. Epub 2021 Nov 1. Nat Biomed Eng. 2021. PMID: 34725507 Free PMC article.
Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.
Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, Zhou Z, Zhang L, Frieden M, Wang L, Luo Z, Radovich M, Schneider BP, Deng Y, Liu Y, Huang K, He B, Wang J, He X, Zhang X, Ji G, Lu X. Li Y, et al. Among authors: zhang l, zhang x. Nat Commun. 2018 Oct 22;9(1):4394. doi: 10.1038/s41467-018-06811-z. Nat Commun. 2018. PMID: 30349055 Free PMC article.
Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer.
Liu Y, Xu J, Choi HH, Han C, Fang Y, Li Y, Van der Jeught K, Xu H, Zhang L, Frieden M, Wang L, Eyvani H, Sun Y, Zhao G, Zhang Y, Liu S, Wan J, Huang C, Ji G, Lu X, He X, Zhang X. Liu Y, et al. Among authors: zhang l, zhang x, zhang y. Nat Commun. 2018 Nov 9;9(1):4718. doi: 10.1038/s41467-018-07264-0. Nat Commun. 2018. PMID: 30413718 Free PMC article.
Targeting SMARCAL1 as a novel strategy for cancer therapy.
Zhang L, Fan S, Liu H, Huang C. Zhang L, et al. Biochem Biophys Res Commun. 2012 Oct 19;427(2):232-5. doi: 10.1016/j.bbrc.2012.09.060. Epub 2012 Sep 17. Biochem Biophys Res Commun. 2012. PMID: 22995303 Review.
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