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A new method for multiancestry polygenic prediction improves performance across diverse populations.
Zhang H, Zhan J, Jin J, Zhang J, Lu W, Zhao R, Ahearn TU, Yu Z, O'Connell J, Jiang Y, Chen T, Okuhara D; 23andMe Research Team; Garcia-Closas M, Lin X, Koelsch BL, Chatterjee N. Zhang H, et al. Among authors: zhang j. Nat Genet. 2023 Oct;55(10):1757-1768. doi: 10.1038/s41588-023-01501-z. Epub 2023 Sep 25. Nat Genet. 2023. PMID: 37749244 Free PMC article.
An Ensemble Penalized Regression Method for Multi-ancestry Polygenic Risk Prediction.
Zhang J, Zhan J, Jin J, Ma C, Zhao R, O'Connell J, Jiang Y; 23andMe Research Team; Koelsch BL, Zhang H, Chatterjee N. Zhang J, et al. Among authors: zhang h. bioRxiv [Preprint]. 2024 Apr 10:2023.03.15.532652. doi: 10.1101/2023.03.15.532652. bioRxiv. 2024. PMID: 36993331 Free PMC article. Updated. Preprint.
MUSSEL: Enhanced Bayesian Polygenic Risk Prediction Leveraging Information across Multiple Ancestry Groups.
Jin J, Zhan J, Zhang J, Zhao R, O'Connell J, Jiang Y; 23andMe Research Team; Buyske S, Gignoux C, Haiman C, Kenny EE, Kooperberg C, North K, Koelsch BL, Wojcik G, Zhang H, Chatterjee N. Jin J, et al. Among authors: zhang j, zhang h. bioRxiv [Preprint]. 2023 Sep 21:2023.04.12.536510. doi: 10.1101/2023.04.12.536510. bioRxiv. 2023. PMID: 37090648 Free PMC article. Updated. Preprint.
MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups.
Jin J, Zhan J, Zhang J, Zhao R, O'Connell J, Jiang Y; 23andMe Research Team; Buyske S, Gignoux C, Haiman C, Kenny EE, Kooperberg C, North K, Koelsch BL, Wojcik G, Zhang H, Chatterjee N. Jin J, et al. Among authors: zhang j, zhang h. Cell Genom. 2024 Apr 10;4(4):100539. doi: 10.1016/j.xgen.2024.100539. Cell Genom. 2024. PMID: 38604127 Free PMC article.
Proteins Associated with Risk of Kidney Function Decline in the General Population.
Grams ME, Surapaneni A, Chen J, Zhou L, Yu Z, Dutta D, Welling PA, Chatterjee N, Zhang J, Arking DE, Chen TK, Rebholz CM, Yu B, Schlosser P, Rhee EP, Ballantyne CM, Boerwinkle E, Lutsey PL, Mosley T, Feldman HI, Dubin RF, Ganz P, Lee H, Zheng Z, Coresh J. Grams ME, et al. Among authors: zhang j. J Am Soc Nephrol. 2021 Sep;32(9):2291-2302. doi: 10.1681/ASN.2020111607. J Am Soc Nephrol. 2021. PMID: 34465608 Free PMC article.
Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk.
Walker KA, Chen J, Zhang J, Fornage M, Yang Y, Zhou L, Grams ME, Tin A, Daya N, Hoogeveen RC, Wu A, Sullivan KJ, Ganz P, Zeger SL, Gudmundsson EF, Emilsson V, Launer LJ, Jennings LL, Gudnason V, Chatterjee N, Gottesman RF, Mosley TH, Boerwinkle E, Ballantyne CM, Coresh J. Walker KA, et al. Among authors: zhang j. Nat Aging. 2021 May;1(5):473-489. doi: 10.1038/s43587-021-00064-0. Epub 2021 May 14. Nat Aging. 2021. PMID: 37118015 Free PMC article.
Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
Ziyatdinov A, Torres J, Alegre-Díaz J, Backman J, Mbatchou J, Turner M, Gaynor SM, Joseph T, Zou Y, Liu D, Wade R, Staples J, Panea R, Popov A, Bai X, Balasubramanian S, Habegger L, Lanche R, Lopez A, Maxwell E, Jones M, García-Ortiz H, Ramirez-Reyes R, Santacruz-Benítez R, Nag A, Smith KR, Damask A, Lin N, Paulding C, Reppell M, Zöllner S, Jorgenson E, Salerno W, Petrovski S, Overton J, Reid J, Thornton TA, Abecasis G, Berumen J, Orozco-Orozco L, Collins R; Regeneron Genetics Center; Mexico City Prospective Study; Baras A, Hill MR, Emberson JR, Marchini J, Kuri-Morales P, Tapia-Conyer R. Ziyatdinov A, et al. Nature. 2023 Oct;622(7984):784-793. doi: 10.1038/s41586-023-06595-3. Epub 2023 Oct 11. Nature. 2023. PMID: 37821707 Free PMC article.
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