Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

164,729 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability.
Shi X, Zhao T, Wang S, Xu S, Liao H, Gao S, Gao Z, Zhang J, Qi D, Zhang Z, Zheng F, Wang Y, Wang Z, Yang M, Yang Q, Yi F, Pang J, Liu X, Zhan P. Shi X, et al. Among authors: zhang j, zhang z. J Med Chem. 2024 Mar 28;67(6):5032-5052. doi: 10.1021/acs.jmedchem.4c00136. Epub 2024 Mar 14. J Med Chem. 2024. PMID: 38482820
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles.
Huang B, Chen W, Zhao T, Li Z, Jiang X, Ginex T, Vílchez D, Luque FJ, Kang D, Gao P, Zhang J, Tian Y, Daelemans D, De Clercq E, Pannecouque C, Zhan P, Liu X. Huang B, et al. Among authors: zhang j. J Med Chem. 2019 Feb 28;62(4):2083-2098. doi: 10.1021/acs.jmedchem.8b01729. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30721060
Overview of Recent Strategic Advances in Medicinal Chemistry.
Wu G, Zhao T, Kang D, Zhang J, Song Y, Namasivayam V, Kongsted J, Pannecouque C, De Clercq E, Poongavanam V, Liu X, Zhan P. Wu G, et al. Among authors: zhang j. J Med Chem. 2019 Nov 14;62(21):9375-9414. doi: 10.1021/acs.jmedchem.9b00359. Epub 2019 May 28. J Med Chem. 2019. PMID: 31050421 Review.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Jia R, Zhang J, Shi F, Bonomini A, Lucca C, Bertagnin C, Zhang J, Liu C, Jia H, Jiang Y, Ma X, Loregian A, Huang B, Zhan P, Liu X. Jia R, et al. Among authors: zhang j. Eur J Med Chem. 2023 Apr 5;252:115275. doi: 10.1016/j.ejmech.2023.115275. Epub 2023 Mar 13. Eur J Med Chem. 2023. PMID: 36931117
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
Zhang J, Liu C, Jia R, Zhang X, Zhang J, Bertagnin C, Bonomini A, Guizzo L, Jiang Y, Jia H, Jia S, Ma X, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: zhang x. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2277135. doi: 10.1080/14756366.2023.2277135. Epub 2023 Nov 13. J Enzyme Inhib Med Chem. 2023. PMID: 37955306 Free PMC article.
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.
Zhang J, Poongavanam V, Kang D, Bertagnin C, Lu H, Kong X, Ju H, Lu X, Gao P, Tian Y, Jia H, Desta S, Ding X, Sun L, Fang Z, Huang B, Liang X, Jia R, Ma X, Xu W, Murugan NA, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. J Med Chem. 2018 Jul 26;61(14):6379-6397. doi: 10.1021/acs.jmedchem.8b00929. Epub 2018 Jul 16. J Med Chem. 2018. PMID: 29965752
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant.
Zhang J, Murugan NA, Tian Y, Bertagnin C, Fang Z, Kang D, Kong X, Jia H, Sun Z, Jia R, Gao P, Poongavanam V, Loregian A, Xu W, Ma X, Ding X, Huang B, Zhan P, Liu X. Zhang J, et al. J Med Chem. 2018 Nov 21;61(22):9976-9999. doi: 10.1021/acs.jmedchem.8b01065. Epub 2018 Nov 6. J Med Chem. 2018. PMID: 30365885
Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.
Kang D, Zhang H, Wang Z, Zhao T, Ginex T, Luque FJ, Yang Y, Wu G, Feng D, Wei F, Zhang J, De Clercq E, Pannecouque C, Chen CH, Lee KH, Murugan NA, Steitz TA, Zhan P, Liu X. Kang D, et al. Among authors: zhang j, zhang h. J Med Chem. 2019 Feb 14;62(3):1484-1501. doi: 10.1021/acs.jmedchem.8b01656. Epub 2019 Jan 18. J Med Chem. 2019. PMID: 30624934 Free PMC article.
164,729 results
You have reached the last available page of results. Please see the User Guide for more information.