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Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants.
Cai Y, Zhang J, Xiao T, Lavine CL, Rawson S, Peng H, Zhu H, Anand K, Tong P, Gautam A, Lu S, Sterling SM, Walsh RM Jr, Rits-Volloch S, Lu J, Wesemann DR, Yang W, Seaman MS, Chen B. Cai Y, et al. Among authors: zhang j. Science. 2021 Aug 6;373(6555):642-648. doi: 10.1126/science.abi9745. Epub 2021 Jun 24. Science. 2021. PMID: 34168070 Free PMC article.
Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant.
Zhang J, Xiao T, Cai Y, Lavine CL, Peng H, Zhu H, Anand K, Tong P, Gautam A, Mayer ML, Walsh RM Jr, Rits-Volloch S, Wesemann DR, Yang W, Seaman MS, Lu J, Chen B. Zhang J, et al. Science. 2021 Dec 10;374(6573):1353-1360. doi: 10.1126/science.abl9463. Epub 2021 Oct 26. Science. 2021. PMID: 34698504 Free PMC article.
Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane.
Shi W, Cai Y, Zhu H, Peng H, Voyer J, Rits-Volloch S, Cao H, Mayer ML, Song K, Xu C, Lu J, Zhang J, Chen B. Shi W, et al. Among authors: zhang j. Nature. 2023 Jul;619(7969):403-409. doi: 10.1038/s41586-023-06273-4. Epub 2023 Jun 7. Nature. 2023. PMID: 37285872
Structural impact on SARS-CoV-2 spike protein by D614G substitution.
Zhang J, Cai Y, Xiao T, Lu J, Peng H, Sterling SM, Walsh RM Jr, Rits-Volloch S, Zhu H, Woosley AN, Yang W, Sliz P, Chen B. Zhang J, et al. Science. 2021 Apr 30;372(6541):525-530. doi: 10.1126/science.abf2303. Epub 2021 Mar 16. Science. 2021. PMID: 33727252 Free PMC article.
Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2.
Kwon HJ, Zhang J, Kosikova M, Tang W, Ortega-Rodriguez U, Peng H, Meseda CA, Pedro CL, Schmeisser F, Lu J, Kang I, Zhou B, Davis CT, Wentworth DE, Chen WH, Shriver MC, Barnes RS, Pasetti MF, Weir JP, Chen B, Xie H. Kwon HJ, et al. Among authors: zhang j. J Med Virol. 2023 Mar;95(3):e28673. doi: 10.1002/jmv.28673. J Med Virol. 2023. PMID: 36916782 Free PMC article.
An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW. Luo S, et al. Among authors: zhang j. Sci Immunol. 2022 Oct 28;7(76):eadd5446. doi: 10.1126/sciimmunol.add5446. Epub 2022 Aug 11. Sci Immunol. 2022. PMID: 35951767 Free PMC article.
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