Zhang J - Search Results

1

Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer.

Cheng C, Wang J, Xu P, Zhang K, Xin Z, Zhao H, Ji Z, Zhang M, Wang D, He Y, Jing N, Fan L, Liu K, Li F, Liu C, Gong Y, Cui S, Sun Z, Sun D, Yao X, Li H, Zhang J, Zhang P, Dong B, Xue W, Qian X, Gao WQ, Zhu HH. Cheng C, et al. Among authors: zhang m, zhang p, zhang j, zhang k. Nat Cancer. 2022 May;3(5):565-580. doi: 10.1038/s43018-022-00380-3. Epub 2022 May 27. Nat Cancer. 2022. PMID: 35624341

2

Identification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma.

Li F, Fang Z, Zhang J, Li C, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li F, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H. Li F, et al. Among authors: zhang w, zhang j. Cell Res. 2016 Oct;26(10):1149-1164. doi: 10.1038/cr.2016.111. Epub 2016 Sep 27. Cell Res. 2016. PMID: 27670699 Free PMC article.

3

Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.

Wang Y, Zhang J, Ren S, Sun D, Huang HY, Wang H, Jin Y, Li F, Zheng C, Yang L, Deng L, Jiang Z, Jiang T, Han X, Hou S, Guo C, Li F, Gao D, Qin J, Gao D, Chen L, Lin SH, Wong KK, Li C, Hu L, Zhou C, Ji H. Wang Y, et al. Among authors: zhang j. Cell Rep. 2019 Jul 9;28(2):512-525.e6. doi: 10.1016/j.celrep.2019.06.026. Cell Rep. 2019. PMID: 31291585 Free article.

4

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design.

Lu S, He X, Yang Z, Chai Z, Zhou S, Wang J, Rehman AU, Ni D, Pu J, Sun J, Zhang J. Lu S, et al. Among authors: zhang j. Nat Commun. 2021 Aug 5;12(1):4721. doi: 10.1038/s41467-021-25020-9. Nat Commun. 2021. PMID: 34354057 Free PMC article.

5

Rational design of a sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors.

Zhong J, Guo Y, Lu S, Song K, Wang Y, Feng L, Zheng Z, Zhang Q, Wei J, Sang P, Shi Y, Cai J, Chen G, Liu CY, Yang X, Zhang J. Zhong J, et al. Among authors: zhang q, zhang j. Nat Commun. 2022 Aug 24;13(1):4961. doi: 10.1038/s41467-022-32612-6. Nat Commun. 2022. PMID: 36002443 Free PMC article.

6

GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages.

Yan J, Zhang Y, Yu H, Zong Y, Wang D, Zheng J, Jin L, Yu X, Liu C, Zhang Y, Jiang F, Zhang R, Fang X, Xu T, Li M, Di J, Lu Y, Ma X, Zhang J, Jia W, Hu C. Yan J, et al. Among authors: zhang r, zhang j, zhang y. Nat Commun. 2022 Nov 25;13(1):7260. doi: 10.1038/s41467-022-34998-9. Nat Commun. 2022. PMID: 36434066 Free PMC article.

7

Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors.

Guo AD, Yan KN, Hu H, Zhai L, Hu TF, Su H, Chi Y, Zha J, Xu Y, Zhao D, Lu X, Xu YJ, Zhang J, Tan M, Chen XH. Guo AD, et al. Among authors: zhang j. Nat Chem. 2023 Jun;15(6):803-814. doi: 10.1038/s41557-023-01196-z. Epub 2023 Apr 27. Nat Chem. 2023. PMID: 37106095

8

Global fungal-host interactome mapping identifies host targets of candidalysin.

Zhang TY, Chen YQ, Tan JC, Zhou JA, Chen WN, Jiang T, Zha JY, Zeng XK, Li BW, Wei LQ, Zou Y, Zhang LY, Hong YM, Wang XL, Zhu RZ, Xu WX, Xi J, Wang QQ, Pan L, Zhang J, Luan Y, Zhu RX, Wang H, Chen C, Liu NN. Zhang TY, et al. Among authors: zhang ly, zhang j. Nat Commun. 2024 Feb 27;15(1):1757. doi: 10.1038/s41467-024-46141-x. Nat Commun. 2024. PMID: 38413612 Free PMC article.

9

Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors.

Yang X, Deng M, Zhang X, Wang Y, Song K, Cong R, Meng L, Zhang J. Yang X, et al. Among authors: zhang j, zhang x. Chem Biol Drug Des. 2019 Dec;94(6):2013-2022. doi: 10.1111/cbdd.13425. Epub 2019 Oct 14. Chem Biol Drug Des. 2019. PMID: 30381889

10

Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate-mediated regulation of cullin-RING ligase and sensitize cancer cells to MLN4924/pevonedistat.

Zhang X, Shi S, Su Y, Yang X, He S, Yang X, Wu J, Zhang J, Rao F. Zhang X, et al. Among authors: zhang j. J Biol Chem. 2020 Jul 24;295(30):10281-10292. doi: 10.1074/jbc.RA120.014375. Epub 2020 Jun 3. J Biol Chem. 2020. PMID: 32493769 Free PMC article.

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