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The CD8α-PILRα interaction maintains CD8+ T cell quiescence.
Zheng L, Han X, Yao S, Zhu Y, Klement J, Wu S, Ji L, Zhu G, Cheng X, Tobiasova Z, Yu W, Huang B, Vesely MD, Wang J, Zhang J, Quinlan E, Chen L. Zheng L, et al. Among authors: zhang j. Science. 2022 May 27;376(6596):996-1001. doi: 10.1126/science.aaz8658. Epub 2022 May 26. Science. 2022. PMID: 35617401
Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy.
Wang J, Sun J, Liu LN, Flies DB, Nie X, Toki M, Zhang J, Song C, Zarr M, Zhou X, Han X, Archer KA, O'Neill T, Herbst RS, Boto AN, Sanmamed MF, Langermann S, Rimm DL, Chen L. Wang J, et al. Among authors: zhang j. Nat Med. 2019 Apr;25(4):656-666. doi: 10.1038/s41591-019-0374-x. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833750 Free PMC article.
PD-1H/VISTA mediates immune evasion in acute myeloid leukemia.
Kim TK, Han X, Hu Q, Vandsemb EN, Fielder CM, Hong J, Kim KW, Mason EF, Plowman RS, Wang J, Wang Q, Zhang JP, Badri T, Sanmamed MF, Zheng L, Zhang T, Alawa J, Lee SW, Zeidan AM, Halene S, Pillai MM, Chandhok NS, Lu J, Xu ML, Gore SD, Chen L. Kim TK, et al. Among authors: zhang jp, zhang t. J Clin Invest. 2024 Feb 1;134(3):e164325. doi: 10.1172/JCI164325. J Clin Invest. 2024. PMID: 38060328 Free PMC article.
Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity.
Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris PC, Pearson MJ, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely MD, Zhang Y, Zhang J, Ji L, Flies DB, Liu L, Langermann S, LaRochelle WJ, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper KA, Sanmamed MF, Chen L. Zhang T, et al. Among authors: zhang q, zhang j, zhang y. Sci Immunol. 2024 Apr 26;9(94):eadh2334. doi: 10.1126/sciimmunol.adh2334. Epub 2024 Apr 26. Sci Immunol. 2024. PMID: 38669316
164,759 results
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