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165,146 results

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A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.
Lu Y, Fan Z, Zhu SJ, Huang X, Zhuang Z, Li Y, Deng Z, Gao L, Hong X, Zhang T, Li L, Sun X, Huang W, Zhang J, Liu Y, Zhang B, Jiang J, Gui F, Wang Z, Li Q, Song S, Huang X, Wu Q, Chen L, Zhou D, Zhang J, Yun CH, Chen L, Deng X. Lu Y, et al. Among authors: zhang b, zhang t, zhang j. EMBO Mol Med. 2022 Jan 11;14(1):e14296. doi: 10.15252/emmm.202114296. Epub 2021 Nov 30. EMBO Mol Med. 2022. PMID: 34845836 Free PMC article.
Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.
Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, Song S, Wang H, Chen L, Zhou D, Liu Q, Ren R, Zhang J, Deng X. Jiang J, et al. Among authors: zhang t, zhang j. Cancer Res. 2017 Jan 1;77(1):175-186. doi: 10.1158/0008-5472.CAN-16-1038. Epub 2016 Oct 10. Cancer Res. 2017. PMID: 27758886
A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors.
Ning N, Yu Y, Wu M, Zhang R, Zhang T, Zhu C, Huang L, Yun CH, Benes CH, Zhang J, Deng X, Chen Q, Ren R. Ning N, et al. Among authors: zhang r, zhang t, zhang j. Cancer Res. 2018 Oct 15;78(20):5949-5957. doi: 10.1158/0008-5472.CAN-18-0455. Epub 2018 Aug 22. Cancer Res. 2018. PMID: 30135190
Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer.
Wang Y, Zhang L, Wei Y, Huang W, Li L, Wu AA, Dastur A, Greninger P, Bray WM, Zhang CS, Li M, Lian W, Hu Z, Wang X, Liu G, Yao L, Guh JH, Chen L, Wang HR, Zhou D, Lin SC, Xu Q, Shen Y, Zhang J, Jurica MS, Benes CH, Deng X. Wang Y, et al. Among authors: zhang l, zhang j, zhang cs. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9. Cell Chem Biol. 2020. PMID: 32649904 Free article.
PIKfyve inhibitors against SARS-CoV-2 and its variants including Omicron.
Su J, Zheng J, Huang W, Zhang Y, Lv C, Zhang B, Jiang L, Cheng T, Yuan Q, Xia N, Zhang J, Li L, Li L, Deng X. Su J, et al. Among authors: zhang b, zhang j, zhang y. Signal Transduct Target Ther. 2022 May 24;7(1):167. doi: 10.1038/s41392-022-01025-8. Signal Transduct Target Ther. 2022. PMID: 35610213 Free PMC article. No abstract available.
Broad spectrum alkynyl inhibitors of T315I Bcr-Abl.
Deng X, Lim SM, Zhang J, Gray NS. Deng X, et al. Among authors: zhang j. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4196-200. doi: 10.1016/j.bmcl.2010.05.043. Epub 2010 May 19. Bioorg Med Chem Lett. 2010. PMID: 20541934 Free PMC article.
Expanding the diversity of allosteric bcr-abl inhibitors.
Deng X, Okram B, Ding Q, Zhang J, Choi Y, Adrián FJ, Wojciechowski A, Zhang G, Che J, Bursulaya B, Cowan-Jacob SW, Rummel G, Sim T, Gray NS. Deng X, et al. Among authors: zhang g, zhang j. J Med Chem. 2010 Oct 14;53(19):6934-46. doi: 10.1021/jm100555f. J Med Chem. 2010. PMID: 20828158 Free PMC article.
165,146 results
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