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Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge.
King RG, Silva-Sanchez A, Peel JN, Botta D, Dickson AM, Pinto AK, Meza-Perez S, Allie SR, Schultz MD, Liu M, Bradley JE, Qiu S, Yang G, Zhou F, Zumaquero E, Simpler TS, Mousseau B, Killian JT Jr, Dean B, Shang Q, Tipper JL, Risley CA, Harrod KS, Feng T, Lee Y, Shiberu B, Krishnan V, Peguillet I, Zhang J, Green TJ, Randall TD, Suschak JJ, Georges B, Brien JD, Lund FE, Roberts MS. King RG, et al. Among authors: zhang j. Vaccines (Basel). 2021 Aug 9;9(8):881. doi: 10.3390/vaccines9080881. Vaccines (Basel). 2021. PMID: 34452006 Free PMC article.
Efficacy and immunogenicity of single-dose AdVAV intranasal anthrax vaccine compared to anthrax vaccine absorbed in an aerosolized spore rabbit challenge model.
Krishnan V, Andersen BH, Shoemaker C, Sivko GS, Tordoff KP, Stark GV, Zhang J, Feng T, Duchars M, Roberts MS. Krishnan V, et al. Among authors: zhang j. Clin Vaccine Immunol. 2015 Apr;22(4):430-9. doi: 10.1128/CVI.00690-14. Epub 2015 Feb 11. Clin Vaccine Immunol. 2015. PMID: 25673303 Free PMC article.
Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 in mice.
King RG, Silva-Sanchez A, Peel JN, Botta D, Meza-Perez S, Allie R, Schultz MD, Liu M, Bradley JE, Qiu S, Yang G, Zhou F, Zumaquero E, Simpler TS, Mousseau B, Killian JT, Dean B, Shang Q, Tipper JL, Risley C, Harrod KS, Feng R, Lee Y, Shiberu B, Krishnan V, Peguillet I, Zhang J, Green T, Randall TD, Georges B, Lund FE, Roberts S. King RG, et al. Among authors: zhang j. bioRxiv [Preprint]. 2020 Oct 11:2020.10.10.331348. doi: 10.1101/2020.10.10.331348. bioRxiv. 2020. PMID: 33052351 Free PMC article. Updated. Preprint.
A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts.
Schultz MD, Suschak JJ, Botta D, Silva-Sanchez A, King RG, Detchemendy TW, Meshram CD, Foote JB, Zhou F, Tipper JL, Zhang J, Harrod KS, Leal SM Jr, Randall TD, Roberts MS, Georges B, Lund FE. Schultz MD, et al. Among authors: zhang j. Hum Vaccin Immunother. 2022 Nov 30;18(6):2127292. doi: 10.1080/21645515.2022.2127292. Epub 2022 Oct 4. Hum Vaccin Immunother. 2022. PMID: 36194255 Free PMC article.
The role of vaccination route with an adenovirus-vectored vaccine in protection, viral control, and transmission in the SARS-CoV-2/K18-hACE2 mouse infection model.
Dickson A, Geerling E, Stone ET, Hassert M, Steffen TL, Makkena T, Smither M, Schwetye KE, Zhang J, Georges B, Roberts MS, Suschak JJ, Pinto AK, Brien JD. Dickson A, et al. Among authors: zhang j. Front Immunol. 2023 Aug 16;14:1188392. doi: 10.3389/fimmu.2023.1188392. eCollection 2023. Front Immunol. 2023. PMID: 37662899 Free PMC article.
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