Zhang J - Search Results

1

Reply to: Binding site for MDL-801 on SIRT6.

Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, Zhang L, Wang C, Lu S, Yang X, He B, Min J, Hu H, Tan M, Xu J, Zhang Q, Zhong J, Sun X, Mao Z, Lin H, Xiao M, Chin YE, Jiang H, Shen H, Xu Y, Chen G, Zhang J. Huang Z, et al. Among authors: zhang l, zhang q, zhang j. Nat Chem Biol. 2021 May;17(5):522-523. doi: 10.1038/s41589-021-00750-5. Epub 2021 Mar 1. Nat Chem Biol. 2021. PMID: 33649600 No abstract available.

2

Improved Method for the Identification and Validation of Allosteric Sites.

Song K, Liu X, Huang W, Lu S, Shen Q, Zhang L, Zhang J. Song K, et al. Among authors: zhang l, zhang j. J Chem Inf Model. 2017 Sep 25;57(9):2358-2363. doi: 10.1021/acs.jcim.7b00014. Epub 2017 Aug 31. J Chem Inf Model. 2017. PMID: 28825477

3

Discovery of hidden allosteric sites as novel targets for allosteric drug design.

Lu S, Ji M, Ni D, Zhang J. Lu S, et al. Among authors: zhang j. Drug Discov Today. 2018 Feb;23(2):359-365. doi: 10.1016/j.drudis.2017.10.001. Epub 2017 Oct 10. Drug Discov Today. 2018. PMID: 29030241 Review.

4

Molecular Dynamics Simulations and Dynamic Network Analysis Reveal the Allosteric Unbinding of Monobody to H-Ras Triggered by R135K Mutation.

Ni D, Song K, Zhang J, Lu S. Ni D, et al. Among authors: zhang j. Int J Mol Sci. 2017 Oct 26;18(11):2249. doi: 10.3390/ijms18112249. Int J Mol Sci. 2017. PMID: 29072601 Free PMC article.

5

New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound.

Yang X, Zhang X, Huang M, Song K, Li X, Huang M, Meng L, Zhang J. Yang X, et al. Among authors: zhang j, zhang x. Sci Rep. 2017 Nov 6;7(1):14572. doi: 10.1038/s41598-017-15260-5. Sci Rep. 2017. PMID: 29109464 Free PMC article.

6

Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85α Regulatory Subunit of PI3Kα: Implication for PI3Kα Activation by Calmodulin.

Ni D, Liu D, Zhang J, Lu S. Ni D, et al. Among authors: zhang j. Int J Mol Sci. 2018 Jan 4;19(1):151. doi: 10.3390/ijms19010151. Int J Mol Sci. 2018. PMID: 29300353 Free PMC article.

7

Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.

Lu S, Zhang J. Lu S, et al. Among authors: zhang j. J Med Chem. 2019 Jan 10;62(1):24-45. doi: 10.1021/acs.jmedchem.7b01844. Epub 2018 Feb 26. J Med Chem. 2019. PMID: 29457894

8

Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit.

Wang G, Zhang M, Jang H, Lu S, Lin S, Chen G, Nussinov R, Zhang J, Gaponenko V. Wang G, et al. Among authors: zhang m, zhang j. Biochemistry. 2018 Mar 27;57(12):1917-1928. doi: 10.1021/acs.biochem.7b01130. Epub 2018 Mar 19. Biochemistry. 2018. PMID: 29494137 Free PMC article.

9

Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy.

Chen Y, Li Z, Xu Z, Tang H, Guo W, Sun X, Zhang W, Zhang J, Wan X, Jiang Y, Mao Z. Chen Y, et al. Among authors: zhang w, zhang j. Cell Death Dis. 2018 Apr 1;9(4):420. doi: 10.1038/s41419-018-0453-9. Cell Death Dis. 2018. PMID: 29549248 Free PMC article.

10

Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction.

Yang X, Zhong J, Zhang Q, Qian J, Song K, Ruan C, Xu J, Ding K, Zhang J. Yang X, et al. Among authors: zhang q, zhang j. J Med Chem. 2018 Sep 13;61(17):8017-8028. doi: 10.1021/acs.jmedchem.8b01112. Epub 2018 Aug 20. J Med Chem. 2018. PMID: 30095910

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