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Digital twins to personalize medicine.
Björnsson B, Borrebaeck C, Elander N, Gasslander T, Gawel DR, Gustafsson M, Jörnsten R, Lee EJ, Li X, Lilja S, Martínez-Enguita D, Matussek A, Sandström P, Schäfer S, Stenmarker M, Sun XF, Sysoev O, Zhang H, Benson M; Swedish Digital Twin Consortium. Björnsson B, et al. Among authors: zhang h. Genome Med. 2019 Dec 31;12(1):4. doi: 10.1186/s13073-019-0701-3. Genome Med. 2019. PMID: 31892363 Free PMC article.
A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.
Bruhn S, Fang Y, Barrenäs F, Gustafsson M, Zhang H, Konstantinell A, Krönke A, Sönnichsen B, Bresnick A, Dulyaninova N, Wang H, Zhao Y, Klingelhöfer J, Ambartsumian N, Beck MK, Nestor C, Bona E, Xiang Z, Benson M. Bruhn S, et al. Among authors: zhang h. Sci Transl Med. 2014 Jan 8;6(218):218ra4. doi: 10.1126/scitranslmed.3007410. Sci Transl Med. 2014. PMID: 24401939 Free PMC article.
Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment.
Gustafsson M, Edström M, Gawel D, Nestor CE, Wang H, Zhang H, Barrenäs F, Tojo J, Kockum I, Olsson T, Serra-Musach J, Bonifaci N, Pujana MA, Ernerudh J, Benson M. Gustafsson M, et al. Among authors: zhang h. Genome Med. 2014 Feb 26;6(2):17. doi: 10.1186/gm534. eCollection 2014. Genome Med. 2014. PMID: 24571673 Free PMC article.
Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases.
Lilja S, Li X, Smelik M, Lee EJ, Loscalzo J, Marthanda PB, Hu L, Magnusson M, Sysoev O, Zhang H, Zhao Y, Sjöwall C, Gawel D, Wang H, Benson M. Lilja S, et al. Among authors: zhang h. Cell Rep Med. 2023 Mar 21;4(3):100956. doi: 10.1016/j.xcrm.2023.100956. Epub 2023 Feb 28. Cell Rep Med. 2023. PMID: 36858042 Free PMC article.
Modules, networks and systems medicine for understanding disease and aiding diagnosis.
Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, Villoslada P, Benson M. Gustafsson M, et al. Among authors: zhang h. Genome Med. 2014 Oct 17;6(10):82. doi: 10.1186/s13073-014-0082-6. eCollection 2014. Genome Med. 2014. PMID: 25473422 Free PMC article.
119,463 results
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