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Advances in the discovery of exosome inhibitors in cancer.
Zhang H, Lu J, Liu J, Zhang G, Lu A. Zhang H, et al. Among authors: zhang g. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. doi: 10.1080/14756366.2020.1754814. J Enzyme Inhib Med Chem. 2020. PMID: 32543905 Free PMC article. Review.
Author Correction: HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis.
Liang C, Li J, Lu C, Xie D, Liu J, Zhong C, Wu X, Dai R, Zhang H, Guan D, Guo B, He B, Li F, He X, Zhang W, Zhang BT, Zhang G, Lu A. Liang C, et al. Among authors: zhang w, zhang g, zhang bt, zhang h. Nat Commun. 2020 Jun 22;11(1):3098. doi: 10.1038/s41467-020-16901-6. Nat Commun. 2020. PMID: 32572032 Free PMC article.
Targeting loop3 of sclerostin preserves its cardiovascular protective action and promotes bone formation.
Yu Y, Wang L, Ni S, Li D, Liu J, Chu HY, Zhang N, Sun M, Li N, Ren Q, Zhuo Z, Zhong C, Xie D, Li Y, Zhang ZK, Zhang H, Li M, Zhang Z, Chen L, Pan X, Xia W, Zhang S, Lu A, Zhang BT, Zhang G. Yu Y, et al. Among authors: zhang n, zhang s, zhang g, zhang z, zhang bt, zhang h, zhang zk. Nat Commun. 2022 Jul 22;13(1):4241. doi: 10.1038/s41467-022-31997-8. Nat Commun. 2022. PMID: 35869074 Free PMC article.
Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice.
Wang L, Yu Y, Ni S, Li D, Liu J, Xie D, Chu HY, Ren Q, Zhong C, Zhang N, Li N, Sun M, Zhang ZK, Zhuo Z, Zhang H, Zhang S, Li M, Xia W, Zhang Z, Chen L, Shang P, Pan X, Lu A, Zhang BT, Zhang G. Wang L, et al. Among authors: zhang n, zhang s, zhang g, zhang z, zhang bt, zhang h, zhang zk. Theranostics. 2022 Jul 18;12(13):5645-5674. doi: 10.7150/thno.63177. eCollection 2022. Theranostics. 2022. PMID: 35966595 Free PMC article.
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer.
Zhang H, Yu S, Ni S, Gubu A, Ma Y, Zhang Y, Li H, Wang Y, Wang L, Zhang Z, Yu Y, Lyu A, Zhang B, Zhang G. Zhang H, et al. Among authors: zhang b, zhang g, zhang z, zhang y. Mol Ther Nucleic Acids. 2023 Nov 10;34:102073. doi: 10.1016/j.omtn.2023.102073. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 38074899 Free PMC article.
Unique quinoline orientations shape the modified aptamer to sclerostin for enhanced binding affinity and bone anabolic potential.
Gubu A, Ma Y, Yu S, Zhang H, Chen Z, Ni S, Abdullah R, Xiao H, Zhang Y, Dai H, Luo H, Yu Y, Wang L, Jiang H, Zhang N, Tian Y, Li H, Lu A, Zhang B, Zhang G. Gubu A, et al. Among authors: zhang n, zhang b, zhang g, zhang h, zhang y. Mol Ther Nucleic Acids. 2024 Feb 13;35(1):102146. doi: 10.1016/j.omtn.2024.102146. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2024. PMID: 38444701 Free PMC article.
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