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Omics analysis of Mycobacterium tuberculosis isolates uncovers Rv3094c, an ethionamide metabolism-associated gene.
Wan L, Hu P, Zhang L, Wang ZX, Fleming J, Ni B, Luo J, Guan CX, Bai L, Tan Y, Liu H, Li N, Xiao T, Bai H, Zhang YA, Zhang XE, Wan K, Bi L, Ouyang S, Zhang H. Wan L, et al. Among authors: zhang l, zhang ya, zhang xe, zhang h. Commun Biol. 2023 Feb 7;6(1):156. doi: 10.1038/s42003-023-04433-w. Commun Biol. 2023. PMID: 36750726 Free PMC article.
Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance.
Zhang H, Li D, Zhao L, Fleming J, Lin N, Wang T, Liu Z, Li C, Galwey N, Deng J, Zhou Y, Zhu Y, Gao Y, Wang T, Wang S, Huang Y, Wang M, Zhong Q, Zhou L, Chen T, Zhou J, Yang R, Zhu G, Hang H, Zhang J, Li F, Wan K, Wang J, Zhang XE, Bi L. Zhang H, et al. Among authors: zhang xe, zhang j. Nat Genet. 2013 Oct;45(10):1255-60. doi: 10.1038/ng.2735. Epub 2013 Sep 1. Nat Genet. 2013. PMID: 23995137
Identification of serum microRNA biomarkers for tuberculosis using RNA-seq.
Zhang H, Sun Z, Wei W, Liu Z, Fleming J, Zhang S, Lin N, Wang M, Chen M, Xu Y, Zhou J, Li C, Bi L, Zhou G. Zhang H, et al. Among authors: zhang s. PLoS One. 2014 Feb 20;9(2):e88909. doi: 10.1371/journal.pone.0088909. eCollection 2014. PLoS One. 2014. PMID: 24586438 Free PMC article.
Mycobacterium tuberculosis type III-A CRISPR/Cas system crRNA and its maturation have atypical features.
Wei W, Zhang S, Fleming J, Chen Y, Li Z, Fan S, Liu Y, Wang W, Wang T, Liu Y, Ren B, Wang M, Jiao J, Chen Y, Zhou Y, Zhou Y, Gu S, Zhang X, Wan L, Chen T, Zhou L, Chen Y, Zhang XE, Li C, Zhang H, Bi L. Wei W, et al. Among authors: zhang s, zhang xe, zhang x, zhang h. FASEB J. 2019 Jan;33(1):1496-1509. doi: 10.1096/fj.201800557RR. Epub 2018 Jul 6. FASEB J. 2019. PMID: 29979631
This study unveils further diversity among CRISPR/Cas systems and provides insight into the crRNA recognition mechanism in M. tuberculosis, providing a foundation for investigating the potential of a type III-A-based genome editing system.-Wei, W., Zhang, S., Fleming, J., …
This study unveils further diversity among CRISPR/Cas systems and provides insight into the crRNA recognition mechanism in M. tuberculosis, …
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