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Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Zhang H, et al. Among authors: zhang hg. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637402 Free PMC article.
Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.
Yuan Y, Miao Y, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L, Chen X, Jin L, Huang F, Zhang H, Zhang W, Li W, Xu G, Zheng H. Yuan Y, et al. Among authors: zhang l, zhang w, zhang h, zhang y. Mol Cell. 2020 Feb 20;77(4):734-747.e7. doi: 10.1016/j.molcel.2019.11.003. Epub 2019 Dec 4. Mol Cell. 2020. PMID: 31812350 Free article.
Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1.
Zhang HG, Guo J, Yuan Y, Zuo Y, Liu J, Zhu L, Miao Y, Chen X, Jin L, Huang F, Ren T, He J, Shi W, Wen Z, Zhu C, Zheng H, Dong C, Qian F. Zhang HG, et al. Front Microbiol. 2020 Nov 19;11:597972. doi: 10.3389/fmicb.2020.597972. eCollection 2020. Front Microbiol. 2020. PMID: 33329486 Free PMC article.
Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3.
Chen X, Xu Y, Tu W, Huang F, Zuo Y, Zhang HG, Jin L, Feng Q, Ren T, He J, Miao Y, Yuan Y, Zhao Q, Liu J, Zhang R, Zhu L, Qian F, Zhu C, Zheng H, Wang J. Chen X, et al. Among authors: zhang r, zhang hg. Immunology. 2021 Jul;163(3):278-292. doi: 10.1111/imm.13315. Epub 2021 Feb 22. Immunology. 2021. PMID: 33513265 Free PMC article.
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
Yuan Y, Miao Y, Ren T, Huang F, Qian L, Chen X, Zuo Y, Zhang HG, He J, Qiao C, Du Q, Wu Q, Zhang W, Zhu C, Xu Y, Wu D, Shi W, Jiang J, Xu G, Zheng H. Yuan Y, et al. Among authors: zhang hg, zhang w. EMBO Rep. 2022 Jan 5;23(1):e53466. doi: 10.15252/embr.202153466. Epub 2021 Nov 15. EMBO Rep. 2022. PMID: 34779558 Free PMC article.
E3 ubiquitin ligase MID1 ubiquitinates and degrades type-I interferon receptor 2.
Chen X, Zhao Q, Xu Y, Wu Q, Zhang R, Du Q, Miao Y, Zuo Y, Zhang HG, Huang F, Ren T, He J, Qiao C, Li Y, Li S, Xu Y, Wu D, Yu Z, Lv H, Wang J, Zheng H, Yuan Y. Chen X, et al. Among authors: zhang r, zhang hg. Immunology. 2022 Nov;167(3):398-412. doi: 10.1111/imm.13544. Epub 2022 Jul 23. Immunology. 2022. PMID: 35794827 Free article.
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Zhang HG, Wang B, Yang Y, Liu X, Wang J, Xin N, Li S, Miao Y, Wu Q, Guo T, Yuan Y, Zuo Y, Chen X, Ren T, Dong C, Wang J, Ruan H, Sun M, Xu X, Zheng H. Zhang HG, et al. Cell Res. 2022 Oct;32(10):897-913. doi: 10.1038/s41422-022-00689-9. Epub 2022 Jul 12. Cell Res. 2022. PMID: 35821088 Free PMC article.
119,387 results
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