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A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, Li Z, Liu S, Feng H, Huang W, Duan R, Xu T, Raj N, Zhang F, Dou J, Xu C, Wu H, Bassell GJ, Warren ST, Allen EG, Jin P, Wen Z. Kang Y, et al. Among authors: zhang f. Nat Neurosci. 2021 Oct;24(10):1377-1391. doi: 10.1038/s41593-021-00913-6. Epub 2021 Aug 19. Nat Neurosci. 2021. PMID: 34413513 Free PMC article.
Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis.
Raj N, McEachin ZT, Harousseau W, Zhou Y, Zhang F, Merritt-Garza ME, Taliaferro JM, Kalinowska M, Marro SG, Hales CM, Berry-Kravis E, Wolf-Ochoa MW, Martinez-Cerdeño V, Wernig M, Chen L, Klann E, Warren ST, Jin P, Wen Z, Bassell GJ. Raj N, et al. Among authors: zhang f. Cell Rep. 2021 Apr 13;35(2):108991. doi: 10.1016/j.celrep.2021.108991. Cell Rep. 2021. PMID: 33852833 Free PMC article.
Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.
Li L, Zang L, Zhang F, Chen J, Shen H, Shu L, Liang F, Feng C, Chen D, Tao H, Xu T, Li Z, Kang Y, Wu H, Tang L, Zhang P, Jin P, Shu Q, Li X. Li L, et al. Among authors: zhang p, zhang f. Hum Mol Genet. 2017 Jul 1;26(13):2398-2411. doi: 10.1093/hmg/ddx128. Hum Mol Genet. 2017. PMID: 28398475 Free PMC article.
Zika virus directly infects peripheral neurons and induces cell death.
Oh Y, Zhang F, Wang Y, Lee EM, Choi IY, Lim H, Mirakhori F, Li R, Huang L, Xu T, Wu H, Li C, Qin CF, Wen Z, Wu QF, Tang H, Xu Z, Jin P, Song H, Ming GL, Lee G. Oh Y, et al. Among authors: zhang f. Nat Neurosci. 2017 Sep;20(9):1209-1212. doi: 10.1038/nn.4612. Epub 2017 Jul 31. Nat Neurosci. 2017. PMID: 28758997 Free PMC article.
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