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OX40 promotes obesity-induced adipose inflammation and insulin resistance.
Liu B, Yu H, Sun G, Sun X, Jin H, Zhang C, Shi W, Tian D, Liu K, Xu H, Li X, Yin J, Hong X, Zhang D. Liu B, et al. Among authors: zhang c, zhang d. Cell Mol Life Sci. 2017 Oct;74(20):3827-3840. doi: 10.1007/s00018-017-2552-7. Epub 2017 Jun 13. Cell Mol Life Sci. 2017. PMID: 28612217
OX40 Regulates Both Innate and Adaptive Immunity and Promotes Nonalcoholic Steatohepatitis.
Sun G, Jin H, Zhang C, Meng H, Zhao X, Wei D, Ou X, Wang Q, Li S, Wang T, Sun X, Shi W, Tian D, Liu K, Xu H, Tian Y, Li X, Guo W, Jia J, Zhang Z, Zhang D. Sun G, et al. Among authors: zhang c, zhang d, zhang z. Cell Rep. 2018 Dec 26;25(13):3786-3799.e4. doi: 10.1016/j.celrep.2018.12.006. Cell Rep. 2018. PMID: 30590049 Free article.
The immunoregulatory effects of CD8 T-cell-derived perforin on diet-induced nonalcoholic steatohepatitis.
Wang T, Sun G, Wang Y, Li S, Zhao X, Zhang C, Jin H, Tian D, Liu K, Shi W, Tian Y, Zhang D. Wang T, et al. Among authors: zhang c, zhang d. FASEB J. 2019 Jul;33(7):8490-8503. doi: 10.1096/fj.201802534RR. Epub 2019 Apr 5. FASEB J. 2019. PMID: 30951375
We have elucidated an important role for the cytotoxic immune effector molecule perforin from CD8 T cells in restricting hepatic inflammation in mice with NASH and suggest that therapies designed to maximize the function of endogenous perforin in CD8 T cells might have potential …
We have elucidated an important role for the cytotoxic immune effector molecule perforin from CD8 T cells in restricting hepatic inflammatio …
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