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Modeling disrupted synapse formation in wolfram syndrome using hESCs-derived neural cells and cerebral organoids identifies Riluzole as a therapeutic molecule.
Yuan F, Li Y, Hu R, Gong M, Chai M, Ma X, Cha J, Guo P, Yang K, Li M, Xu M, Ma Q, Su Q, Zhang C, Sheng Z, Wu H, Wang Y, Yuan W, Bian S, Shao L, Zhang R, Li K, Shao Z, Zhang ZN, Li W. Yuan F, et al. Among authors: zhang zn, zhang r, zhang c. Mol Psychiatry. 2023 Apr;28(4):1557-1570. doi: 10.1038/s41380-023-01987-3. Epub 2023 Feb 7. Mol Psychiatry. 2023. PMID: 36750736 Free PMC article.
Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X. Hong T, et al. Among authors: zhang c. Signal Transduct Target Ther. 2024 May 13;9(1):111. doi: 10.1038/s41392-024-01821-4. Signal Transduct Target Ther. 2024. PMID: 38735995
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