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Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1.
Shao Z, Shen Q, Yao B, Mao C, Chen LN, Zhang H, Shen DD, Zhang C, Li W, Du X, Li F, Ma H, Chen ZH, Xu HE, Ying S, Zhang Y, Shen H. Shao Z, et al. Among authors: zhang c, zhang h, zhang y. Nat Chem Biol. 2022 Mar;18(3):264-271. doi: 10.1038/s41589-021-00918-z. Epub 2021 Dec 23. Nat Chem Biol. 2022. PMID: 34949837 Free PMC article.
Eosinophilic inflammation promotes CCL6-dependent metastatic tumor growth.
Li F, Du X, Lan F, Li N, Zhang C, Zhu C, Wang X, He Y, Shao Z, Chen H, Luo M, Li W, Chen Z, Ying S, Shen H. Li F, et al. Among authors: zhang c. Sci Adv. 2021 May 26;7(22):eabb5943. doi: 10.1126/sciadv.abb5943. Print 2021 May. Sci Adv. 2021. PMID: 34039594 Free PMC article.
Ligand recognition, unconventional activation, and G protein coupling of the prostaglandin E2 receptor EP2 subtype.
Qu C, Mao C, Xiao P, Shen Q, Zhong YN, Yang F, Shen DD, Tao X, Zhang H, Yan X, Zhao RJ, He J, Guan Y, Zhang C, Hou G, Zhang PJ, Hou G, Li Z, Yu X, Chai RJ, Guan YF, Sun JP, Zhang Y. Qu C, et al. Among authors: zhang pj, zhang c, zhang h, zhang y. Sci Adv. 2021 Apr 2;7(14):eabf1268. doi: 10.1126/sciadv.abf1268. Print 2021 Apr. Sci Adv. 2021. PMID: 33811074 Free PMC article.
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors.
Zhao F, Zhou Q, Cong Z, Hang K, Zou X, Zhang C, Chen Y, Dai A, Liang A, Ming Q, Wang M, Chen LN, Xu P, Chang R, Feng W, Xia T, Zhang Y, Wu B, Yang D, Zhao L, Xu HE, Wang MW. Zhao F, et al. Among authors: zhang c, zhang y. Nat Commun. 2022 Feb 25;13(1):1057. doi: 10.1038/s41467-022-28683-0. Nat Commun. 2022. PMID: 35217653 Free PMC article.
Structural basis for the tethered peptide activation of adhesion GPCRs.
Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, Zhang DL, Zhu ZL, Jiang Y, Du L, Feng SQ, Schöneberg T, Liebscher I, Xu HE, Sun JP. Ping YQ, et al. Among authors: zhang c, zhang dl. Nature. 2022 Apr;604(7907):763-770. doi: 10.1038/s41586-022-04619-y. Epub 2022 Apr 13. Nature. 2022. PMID: 35418678
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