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Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B. Jiang L, et al. Among authors: zhang c. Mol Cell. 2021 Oct 21;81(20):4209-4227.e12. doi: 10.1016/j.molcel.2021.07.038. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453888 Free PMC article.
Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Apicco DJ, et al. Among authors: zhang c. Nat Neurosci. 2018 Jan;21(1):72-80. doi: 10.1038/s41593-017-0022-z. Epub 2017 Nov 20. Nat Neurosci. 2018. PMID: 29273772 Free PMC article.
RNA binding proteins co-localize with small tau inclusions in tauopathy.
Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. Maziuk BF, et al. Among authors: zhang c. Acta Neuropathol Commun. 2018 Aug 1;6(1):71. doi: 10.1186/s40478-018-0574-5. Acta Neuropathol Commun. 2018. PMID: 30068389 Free PMC article.
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy.
Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, Zhang C, Dong H, Mutter RW, Lou Z. Tu X, et al. Among authors: zhang c, zhang y. Mol Cell. 2019 Jun 20;74(6):1215-1226.e4. doi: 10.1016/j.molcel.2019.04.005. Epub 2019 Apr 30. Mol Cell. 2019. PMID: 31053471 Free PMC article.
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