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The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.
Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B. Wang M, et al. Among authors: zhang b. Sci Data. 2018 Sep 11;5:180185. doi: 10.1038/sdata.2018.185. Sci Data. 2018. PMID: 30204156 Free PMC article.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.
Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S. Audrain M, et al. Among authors: zhang b. Mol Psychiatry. 2019 Sep;24(9):1383-1397. doi: 10.1038/s41380-018-0258-3. Epub 2018 Oct 3. Mol Psychiatry. 2019. PMID: 30283031 Free PMC article.
GJA1 (connexin43) is a key regulator of Alzheimer's disease pathogenesis.
Kajiwara Y, Wang E, Wang M, Sin WC, Brennand KJ, Schadt E, Naus CC, Buxbaum J, Zhang B. Kajiwara Y, et al. Among authors: zhang b. Acta Neuropathol Commun. 2018 Dec 21;6(1):144. doi: 10.1186/s40478-018-0642-x. Acta Neuropathol Commun. 2018. PMID: 30577786 Free PMC article.
Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.
Bai B, Wang X, Li Y, Chen PC, Yu K, Dey KK, Yarbro JM, Han X, Lutz BM, Rao S, Jiao Y, Sifford JM, Han J, Wang M, Tan H, Shaw TI, Cho JH, Zhou S, Wang H, Niu M, Mancieri A, Messler KA, Sun X, Wu Z, Pagala V, High AA, Bi W, Zhang H, Chi H, Haroutunian V, Zhang B, Beach TG, Yu G, Peng J. Bai B, et al. Among authors: zhang b, zhang h. Neuron. 2020 Mar 18;105(6):975-991.e7. doi: 10.1016/j.neuron.2019.12.015. Epub 2020 Jan 8. Neuron. 2020. PMID: 31926610 Free PMC article.
Systems modeling of white matter microstructural abnormalities in Alzheimer's disease.
Horgusluoglu-Moloch E, Xiao G, Wang M, Wang Q, Zhou X, Nho K, Saykin AJ, Schadt E, Zhang B; Alzheimer's Disease Neuroimaging Initiative (ADNI). Horgusluoglu-Moloch E, et al. Among authors: zhang b. Neuroimage Clin. 2020;26:102203. doi: 10.1016/j.nicl.2020.102203. Epub 2020 Feb 4. Neuroimage Clin. 2020. PMID: 32062565 Free PMC article.
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