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Targeting ACLY efficiently inhibits SARS-CoV-2 replication.
Yuen TT, Chan JF, Yan B, Shum CC, Liu Y, Shuai H, Hou Y, Huang X, Hu B, Chai Y, Yoon C, Zhu T, Liu H, Shi J, Zhang J, Cai JP, Zhang AJ, Zhou J, Yin F, Yuan S, Zhang BZ, Chu H. Yuen TT, et al. Among authors: zhang bz, zhang aj, zhang j. Int J Biol Sci. 2022 Jul 11;18(12):4714-4730. doi: 10.7150/ijbs.72709. eCollection 2022. Int J Biol Sci. 2022. PMID: 35874959 Free PMC article.
Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial.
Hung IF, Zhang AJ, To KK, Chan JF, Li P, Wong TL, Zhang R, Chan TC, Chan BC, Wai HH, Chan LW, Fong HP, Hui RK, Kong KL, Leung AC, Ngan AH, Tsang LW, Yeung AP, Yiu GC, Yung W, Lau JY, Chen H, Chan KH, Yuen KY. Hung IF, et al. Among authors: zhang r, zhang aj. Lancet Infect Dis. 2016 Feb;16(2):209-18. doi: 10.1016/S1473-3099(15)00354-0. Epub 2015 Nov 9. Lancet Infect Dis. 2016. PMID: 26559482 Clinical Trial.
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.
Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY. Chan JF, et al. Among authors: zhang aj. Emerg Microbes Infect. 2016 Aug 24;5(8):e93. doi: 10.1038/emi.2016.99. Emerg Microbes Infect. 2016. PMID: 27553173 Free PMC article.
Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons.
Chan JF, Zhang AJ, Chan CC, Yip CC, Mak WW, Zhu H, Poon VK, Tee KM, Zhu Z, Cai JP, Tsang JO, Chik KK, Yin F, Chan KH, Kok KH, Jin DY, Au-Yeung RK, Yuen KY. Chan JF, et al. Among authors: zhang aj. EBioMedicine. 2016 Dec;14:112-122. doi: 10.1016/j.ebiom.2016.11.017. Epub 2016 Nov 12. EBioMedicine. 2016. PMID: 27884655 Free PMC article.
Improved detection of Zika virus RNA in human and animal specimens by a novel, highly sensitive and specific real-time RT-PCR assay targeting the 5'-untranslated region of Zika virus.
Chan JF, Yip CC, Tee KM, Zhu Z, Tsang JO, Chik KK, Tsang TG, Chan CC, Poon VK, Sridhar S, Yin F, Hung IF, Chau SK, Zhang AJ, Chan KH, Yuen KY. Chan JF, et al. Among authors: zhang aj. Trop Med Int Health. 2017 May;22(5):594-603. doi: 10.1111/tmi.12857. Epub 2017 Mar 16. Trop Med Int Health. 2017. PMID: 28214373 Free article.
Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.
Yuan S, Chan JF, den-Haan H, Chik KK, Zhang AJ, Chan CC, Poon VK, Yip CC, Mak WW, Zhu Z, Zou Z, Tee KM, Cai JP, Chan KH, de la Peña J, Pérez-Sánchez H, Cerón-Carrasco JP, Yuen KY. Yuan S, et al. Among authors: zhang aj. Antiviral Res. 2017 Sep;145:33-43. doi: 10.1016/j.antiviral.2017.07.007. Epub 2017 Jul 14. Antiviral Res. 2017. PMID: 28712942
Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.
Guo Q, Chan JF, Poon VK, Wu S, Chan CC, Hou L, Yip CC, Ren C, Cai JP, Zhao M, Zhang AJ, Song X, Chan KH, Wang B, Kok KH, Wen Y, Yuen KY, Chen W. Guo Q, et al. Among authors: zhang aj. J Infect Dis. 2018 Jul 2;218(3):365-377. doi: 10.1093/infdis/jiy187. J Infect Dis. 2018. PMID: 29617816
271 results