Zhai L - Search Results

1

Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.

Zhai L, Bell A, Ladomersky E, Lauing KL, Bollu L, Sosman JA, Zhang B, Wu JD, Miller SD, Meeks JJ, Lukas RV, Wyatt E, Doglio L, Schiltz GE, McCusker RH, Wainwright DA. Zhai L, et al. Front Immunol. 2020 Jun 16;11:1185. doi: 10.3389/fimmu.2020.01185. eCollection 2020. Front Immunol. 2020. PMID: 32612606 Free PMC article. Review.

2

The role of IDO in brain tumor immunotherapy.

Zhai L, Lauing KL, Chang AL, Dey M, Qian J, Cheng Y, Lesniak MS, Wainwright DA. Zhai L, et al. J Neurooncol. 2015 Jul;123(3):395-403. doi: 10.1007/s11060-014-1687-8. Epub 2014 Dec 18. J Neurooncol. 2015. PMID: 25519303 Free PMC article. Review.

3

The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy.

Zhai L, Dey M, Lauing KL, Gritsina G, Kaur R, Lukas RV, Nicholas MK, Rademaker AW, Dostal CR, McCusker RH, Raizer JJ, Parsa AT, Bloch O, Wainwright DA. Zhai L, et al. J Clin Neurosci. 2015 Dec;22(12):1964-8. doi: 10.1016/j.jocn.2015.06.018. Epub 2015 Aug 14. J Clin Neurosci. 2015. PMID: 26279502 Free PMC article.

4

Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.

Zhai L, Spranger S, Binder DC, Gritsina G, Lauing KL, Giles FJ, Wainwright DA. Zhai L, et al. Clin Cancer Res. 2015 Dec 15;21(24):5427-33. doi: 10.1158/1078-0432.CCR-15-0420. Epub 2015 Oct 30. Clin Cancer Res. 2015. PMID: 26519060 Free PMC article. Review.

5

Advanced age negatively impacts survival in an experimental brain tumor model.

Ladomersky E, Zhai L, Gritsina G, Genet M, Lauing KL, Wu M, James CD, Wainwright DA. Ladomersky E, et al. Among authors: zhai l. Neurosci Lett. 2016 Sep 6;630:203-208. doi: 10.1016/j.neulet.2016.08.002. Epub 2016 Aug 1. Neurosci Lett. 2016. PMID: 27493076 Free PMC article.

6

Improving vaccine efficacy against malignant glioma.

Ladomersky E, Genet M, Zhai L, Gritsina G, Lauing KL, Lulla RR, Fangusaro J, Lenzen A, Kumthekar P, Raizer JJ, Binder DC, James CD, Wainwright DA. Ladomersky E, et al. Among authors: zhai l. Oncoimmunology. 2016 Jun 10;5(8):e1196311. doi: 10.1080/2162402X.2016.1196311. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622066 Free PMC article. Review.

7

The Kynurenine/Tryptophan Ratio and Glioblastoma Patients Treated with Hsppc-96 Vaccine.

Lenzen A, Zhai L, Lauing KL, Gritsina G, Ladomersky E, Genet M, James CD, Bloch O, Wainwright DA. Lenzen A, et al. Among authors: zhai l. Immunotherapy (Los Angel). 2016 Sep;2(3):125. doi: 10.4172/2471-9552.1000125. Epub 2016 Sep 9. Immunotherapy (Los Angel). 2016. PMID: 27819068 Free PMC article.

8

Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.

Zhai L, Ladomersky E, Dostal CR, Lauing KL, Swoap K, Billingham LK, Gritsina G, Wu M, McCusker RH, Binder DC, Wainwright DA. Zhai L, et al. Brain Behav Immun. 2017 May;62:24-29. doi: 10.1016/j.bbi.2017.01.022. Epub 2017 Feb 4. Brain Behav Immun. 2017. PMID: 28179106 Free PMC article.

9

Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival.

Zhai L, Ladomersky E, Lauing KL, Wu M, Genet M, Gritsina G, Győrffy B, Brastianos PK, Binder DC, Sosman JA, Giles FJ, James CD, Horbinski C, Stupp R, Wainwright DA. Zhai L, et al. Clin Cancer Res. 2017 Nov 1;23(21):6650-6660. doi: 10.1158/1078-0432.CCR-17-0120. Epub 2017 Jul 27. Clin Cancer Res. 2017. PMID: 28751450 Free PMC article.

10

IDO1 in cancer: a Gemini of immune checkpoints.

Zhai L, Ladomersky E, Lenzen A, Nguyen B, Patel R, Lauing KL, Wu M, Wainwright DA. Zhai L, et al. Cell Mol Immunol. 2018 May;15(5):447-457. doi: 10.1038/cmi.2017.143. Epub 2018 Jan 29. Cell Mol Immunol. 2018. PMID: 29375124 Free PMC article. Review.

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