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A conformational switch controlling the toxicity of the prion protein.
Frontzek K, Bardelli M, Senatore A, Henzi A, Reimann RR, Bedir S, Marino M, Hussain R, Jurt S, Meisl G, Pedotti M, Mazzola F, Siligardi G, Zerbe O, Losa M, Knowles T, Lakkaraju A, Zhu C, Schwarz P, Hornemann S, Holt MG, Simonelli L, Varani L, Aguzzi A. Frontzek K, et al. Among authors: zerbe o. Nat Struct Mol Biol. 2022 Aug;29(8):831-840. doi: 10.1038/s41594-022-00814-7. Epub 2022 Aug 10. Nat Struct Mol Biol. 2022. PMID: 35948768 Free PMC article.
Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Schuster M, Brabet E, Oi KK, Desjonquères N, Moehle K, Le Poupon K, Hell S, Gable S, Rithié V, Dillinger S, Zbinden P, Luther A, Li C, Stiegeler S, D'Arco C, Locher H, Remus T, DiMaio S, Motta P, Wach A, Jung F, Upert G, Obrecht D, Benghezal M, Zerbe O. Schuster M, et al. Among authors: zerbe o. Sci Adv. 2023 May 24;9(21):eadg3683. doi: 10.1126/sciadv.adg3683. Epub 2023 May 24. Sci Adv. 2023. PMID: 37224246 Free PMC article.
Solution Structure and Dynamics of LptE from Pseudomonas aeruginosa.
Moehle K, Kocherla H, Bacsa B, Jurt S, Zerbe K, Robinson JA, Zerbe O. Moehle K, et al. Among authors: zerbe k, zerbe o. Biochemistry. 2016 May 31;55(21):2936-43. doi: 10.1021/acs.biochem.6b00313. Epub 2016 May 19. Biochemistry. 2016. PMID: 27166502
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.
Fumagalli F, Noack J, Bergmann TJ, Cebollero E, Pisoni GB, Fasana E, Fregno I, Galli C, Loi M, Soldà T, D'Antuono R, Raimondi A, Jung M, Melnyk A, Schorr S, Schreiber A, Simonelli L, Varani L, Wilson-Zbinden C, Zerbe O, Hofmann K, Peter M, Quadroni M, Zimmermann R, Molinari M. Fumagalli F, et al. Among authors: zerbe o. Nat Cell Biol. 2016 Nov;18(11):1173-1184. doi: 10.1038/ncb3423. Epub 2016 Oct 17. Nat Cell Biol. 2016. PMID: 27749824
A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D. Wang J, et al. Among authors: zerbe o. Cell. 2017 Sep 21;171(1):229-241.e15. doi: 10.1016/j.cell.2017.09.002. Cell. 2017. PMID: 28938115 Free PMC article.
126 results