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Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19.
Hersi F, Sebastian A, Tarazi H, Srinivasulu V, Mostafa A, Allayeh AK, Zeng C, Hachim IY, Liu SL, Abu-Yousef IA, Majdalawieh AF, Zaher DM, Omar HA, Al-Tel TH. Hersi F, et al. Among authors: zeng c. Eur J Med Chem. 2023 Jun 5;254:115380. doi: 10.1016/j.ejmech.2023.115380. Epub 2023 Apr 17. Eur J Med Chem. 2023. PMID: 37075625 Free PMC article.
SARS-CoV-2 spreads through cell-to-cell transmission.
Zeng C, Evans JP, King T, Zheng YM, Oltz EM, Whelan SPJ, Saif LJ, Peeples ME, Liu SL. Zeng C, et al. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2111400119. doi: 10.1073/pnas.2111400119. Proc Natl Acad Sci U S A. 2022. PMID: 34937699 Free PMC article.
Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
Cui Z, Zeng C, Huang F, Yuan F, Yan J, Zhao Y, Zhou Y, Hankey W, Jin VX, Huang J, Staats HF, Everitt JI, Sempowski GD, Wang H, Dong Y, Liu SL, Wang Q. Cui Z, et al. Among authors: zeng c. Nat Chem Biol. 2022 Oct;18(10):1056-1064. doi: 10.1038/s41589-022-01094-4. Epub 2022 Jul 25. Nat Chem Biol. 2022. PMID: 35879545 Free PMC article.
Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H.
Zeng C, Evans JP, Faraone JN, Qu P, Zheng YM, Saif L, Oltz EM, Lozanski G, Gumina RJ, Liu SL. Zeng C, et al. mBio. 2021 Oct 26;12(5):e0251021. doi: 10.1128/mBio.02510-21. Epub 2021 Oct 5. mBio. 2021. PMID: 34607452 Free PMC article.
4,323 results