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Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors.
J Med Chem. 2018 Sep 13;61(17):7560-7572. doi: 10.1021/acs.jmedchem.7b01847. Epub 2018 Aug 23.
J Med Chem. 2018.
PMID: 30095246
Targeting carnitine biosynthesis: discovery of new inhibitors against γ-butyrobetaine hydroxylase.
Tars K, Leitans J, Kazaks A, Zelencova D, Liepinsh E, Kuka J, Makrecka M, Lola D, Andrianovs V, Gustina D, Grinberga S, Liepinsh E, Kalvinsh I, Dambrova M, Loza E, Pugovics O.
Tars K, et al. Among authors: zelencova d.
J Med Chem. 2014 Mar 27;57(6):2213-36. doi: 10.1021/jm401603e. Epub 2014 Mar 14.
J Med Chem. 2014.
PMID: 24571165
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BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the ability to bind glutathione.
Brangulis K, Akopjana I, Petrovskis I, Kazaks A, Zelencova D, Jekabsons A, Jaudzems K, Tars K.
Brangulis K, et al. Among authors: zelencova d.
Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129499. doi: 10.1016/j.bbagen.2019.129499. Epub 2019 Nov 27.
Biochim Biophys Acta Gen Subj. 2020.
PMID: 31785327
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