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Azithromycin disrupts apicoplast biogenesis in replicating and dormant liver stages of the relapsing malaria parasites Plasmodium vivax and Plasmodium cynomolgi.
Amanzougaghene N, Tajeri S, Franetich JF, Ashraf K, Soulard V, Bigeard P, Guindo CO, Bouillier C, Lemaitre J, Relouzat F, Legrand R, Kocken CHM, Zeeman AM, Roobsoong W, Sattabongkot J, Yang Z, Snounou G, Mazier D. Amanzougaghene N, et al. Among authors: zeeman am. Int J Antimicrob Agents. 2024 May;63(5):107112. doi: 10.1016/j.ijantimicag.2024.107112. Epub 2024 Feb 15. Int J Antimicrob Agents. 2024. PMID: 38367843 Free article.
Epigenetically regulated RNA-binding proteins signify malaria hypnozoite dormancy.
Toenhake CG, Voorberg-van der Wel A, Wu H, Kanyal A, Nieuwenhuis IG, van der Werff NM, Hofman SO, Zeeman AM, Kocken CHM, Bártfai R. Toenhake CG, et al. Among authors: zeeman am. Cell Rep. 2023 Jul 25;42(7):112727. doi: 10.1016/j.celrep.2023.112727. Epub 2023 Jun 30. Cell Rep. 2023. PMID: 37392389 Free article.
Sterile protection against relapsing malaria with a single-shot vaccine.
Pasini EM, van der Wel AV, Heijmans N, Klop O, Zeeman AM, Oostermeijer H, Nieuwenhuis I, Garcia RR, van der Werff NO, Hofman SO, Verreck FAW, Remarque EJ, Faber BW, Kocken CHM. Pasini EM, et al. Among authors: zeeman am. NPJ Vaccines. 2022 Oct 27;7(1):126. doi: 10.1038/s41541-022-00555-0. NPJ Vaccines. 2022. PMID: 36302860 Free PMC article.
Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12).
Dong Y, Sonawane Y, Maher SP, Zeeman AM, Chaumeau V, Vantaux A, Cooper CA, Chiu FCK, Ryan E, McLaren J, Chen G, Wittlin S, Witkowski B, Nosten F, Sriraghavan K, Kyle DE, Kocken CHM, Charman SA, Vennerstrom JL. Dong Y, et al. Among authors: zeeman am. ACS Omega. 2022 Mar 30;7(14):12401-12411. doi: 10.1021/acsomega.2c01099. eCollection 2022 Apr 12. ACS Omega. 2022. PMID: 35449901 Free PMC article.
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Ellis KM, Lucantoni L, Chavchich M, Abraham M, De Paoli A, Luth MR, Zeeman AM, Delves MJ, Terán FS, Straschil U, Baum J, Kocken CHM, Ralph SA, Winzeler EA, Avery VM, Edstein MD, Baell JB, Creek DJ. Ellis KM, et al. Among authors: zeeman am. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0031121. doi: 10.1128/AAC.00311-21. Epub 2021 Aug 30. Antimicrob Agents Chemother. 2021. PMID: 34460304 Free PMC article.
49 results