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Climacostol reduces tumour progression in a mouse model of melanoma via the p53-dependent intrinsic apoptotic programme.
Perrotta C, Buonanno F, Zecchini S, Giavazzi A, Proietti Serafini F, Catalani E, Guerra L, Belardinelli MC, Picchietti S, Fausto AM, Giorgi S, Marcantoni E, Clementi E, Ortenzi C, Cervia D. Perrotta C, et al. Among authors: zecchini s. Sci Rep. 2016 Jun 7;6:27281. doi: 10.1038/srep27281. Sci Rep. 2016. PMID: 27271364 Free PMC article.
Natural products from aquatic eukaryotic microorganisms for cancer therapy: Perspectives on anti-tumour properties of ciliate bioactive molecules.
Catalani E, Proietti Serafini F, Zecchini S, Picchietti S, Fausto AM, Marcantoni E, Buonanno F, Ortenzi C, Perrotta C, Cervia D. Catalani E, et al. Among authors: zecchini s. Pharmacol Res. 2016 Nov;113(Pt A):409-420. doi: 10.1016/j.phrs.2016.09.018. Epub 2016 Sep 17. Pharmacol Res. 2016. PMID: 27650755 Review.
Reversal of Defective Mitochondrial Biogenesis in Limb-Girdle Muscular Dystrophy 2D by Independent Modulation of Histone and PGC-1α Acetylation.
Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C. Pambianco S, et al. Among authors: zecchini s. Cell Rep. 2016 Dec 13;17(11):3010-3023. doi: 10.1016/j.celrep.2016.11.044. Cell Rep. 2016. PMID: 27974213 Free article.
Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition.
Perrotta C, Cervia D, Di Renzo I, Moscheni C, Bassi MT, Campana L, Martelli C, Catalani E, Giovarelli M, Zecchini S, Coazzoli M, Capobianco A, Ottobrini L, Lucignani G, Rosa P, Rovere-Querini P, De Palma C, Clementi E. Perrotta C, et al. Among authors: zecchini s. Front Immunol. 2018 May 29;9:1186. doi: 10.3389/fimmu.2018.01186. eCollection 2018. Front Immunol. 2018. PMID: 29896202 Free PMC article.
The Natural Compound Climacostol as a Prodrug Strategy Based on pH Activation for Efficient Delivery of Cytotoxic Small Agents.
Catalani E, Buonanno F, Lupidi G, Bongiorni S, Belardi R, Zecchini S, Giovarelli M, Coazzoli M, De Palma C, Perrotta C, Clementi E, Prantera G, Marcantoni E, Ortenzi C, Fausto AM, Picchietti S, Cervia D. Catalani E, et al. Among authors: zecchini s. Front Chem. 2019 Jun 28;7:463. doi: 10.3389/fchem.2019.00463. eCollection 2019. Front Chem. 2019. PMID: 31316972 Free PMC article.
XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death.
Muñoz D, Brucoli M, Zecchini S, Sandoval-Hernandez A, Arboleda G, Lopez-Vallejo F, Delgado W, Giovarelli M, Coazzoli M, Catalani E, De Palma C, Perrotta C, Cuca L, Clementi E, Cervia D. Muñoz D, et al. Among authors: zecchini s. Cancers (Basel). 2019 Sep 9;11(9):1336. doi: 10.3390/cancers11091336. Cancers (Basel). 2019. PMID: 31505859 Free PMC article.
36 results