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Comparison of partial least square, artificial neural network, and support vector regressions for real-time monitoring of CHO cell culture processes using in situ near-infrared spectroscopy.
Biotechnol Bioeng. 2022 Feb;119(2):535-549. doi: 10.1002/bit.27997. Epub 2021 Dec 6.
Biotechnol Bioeng. 2022.
PMID: 34821379
In situ cell differentiation monitoring of Catharanthus roseus suspension culture processes by NIR spectroscopy.
Zavala-Ortiz DA, Ebel B, Guedon E, Marc A, Barradas-Dermitz DM, Hayward-Jones PM, Aguilar-Uscanga MG.
Zavala-Ortiz DA, et al.
Bioprocess Biosyst Eng. 2020 Apr;43(4):747-752. doi: 10.1007/s00449-019-02255-x. Epub 2019 Nov 22.
Bioprocess Biosyst Eng. 2020.
PMID: 31758239
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Interest of locally weighted regression to overcome nonlinear effects during in situ NIR monitoring of CHO cell culture parameters and antibody glycosylation.
Zavala-Ortiz DA, Ebel B, Li MY, Barradas-Dermitz DM, Hayward-Jones PM, Aguilar-Uscanga MG, Marc A, Guedon E.
Zavala-Ortiz DA, et al.
Biotechnol Prog. 2020 Jan;36(1):e2924. doi: 10.1002/btpr.2924. Epub 2019 Oct 14.
Biotechnol Prog. 2020.
PMID: 31587521
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