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High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
Kucharska I, Binter Š, Murugan R, Scally SW, Ludwig J, Prieto K, Thai E, Costa G, Li K, Horn GQ, Flores-Garcia Y, Bosch A, Sicard T, Rubinstein JL, Zavala F, Dennison SM, Tomaras GD, Levashina EA, Kellam P, Wardemann H, Julien JP. Kucharska I, et al. Among authors: zavala f. PLoS Pathog. 2022 Nov 28;18(11):e1010999. doi: 10.1371/journal.ppat.1010999. eCollection 2022 Nov. PLoS Pathog. 2022. PMID: 36441829 Free PMC article.
The Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Preerythrocytic and Transmission-Blocking Vaccines.
Espinosa DA, Vega-Rodriguez J, Flores-Garcia Y, Noe AR, Muñoz C, Coleman R, Bruck T, Haney K, Stevens A, Retallack D, Allen J, Vedvick TS, Fox CB, Reed SG, Howard RF, Salman AM, Janse CJ, Khan SM, Zavala F, Gutierrez GM. Espinosa DA, et al. Among authors: zavala f. Infect Immun. 2017 Jan 26;85(2):e00498-16. doi: 10.1128/IAI.00498-16. Print 2017 Feb. Infect Immun. 2017. PMID: 27895131 Free PMC article.
Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
Oyen D, Torres JL, Wille-Reece U, Ockenhouse CF, Emerling D, Glanville J, Volkmuth W, Flores-Garcia Y, Zavala F, Ward AB, King CR, Wilson IA. Oyen D, et al. Among authors: zavala f. Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10438-E10445. doi: 10.1073/pnas.1715812114. Epub 2017 Nov 14. Proc Natl Acad Sci U S A. 2017. PMID: 29138320 Free PMC article.
A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Kisalu NK, Idris AH, Weidle C, Flores-Garcia Y, Flynn BJ, Sack BK, Murphy S, Schön A, Freire E, Francica JR, Miller AB, Gregory J, March S, Liao HX, Haynes BF, Wiehe K, Trama AM, Saunders KO, Gladden MA, Monroe A, Bonsignori M, Kanekiyo M, Wheatley AK, McDermott AB, Farney SK, Chuang GY, Zhang B, Kc N, Chakravarty S, Kwong PD, Sinnis P, Bhatia SN, Kappe SHI, Sim BKL, Hoffman SL, Zavala F, Pancera M, Seder RA. Kisalu NK, et al. Among authors: zavala f. Nat Med. 2018 May;24(4):408-416. doi: 10.1038/nm.4512. Epub 2018 Mar 19. Nat Med. 2018. PMID: 29554083 Free PMC article.
247 results