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CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma.
Hoffmann F, Franzen A, de Vos L, Wuest L, Kulcsár Z, Fietz S, Maas AP, Hollick S, Diop MY, Gabrielpillai J, Vogt T, Kuster P, Zarbl R, Dietrich J, Kristiansen G, Brossart P, Landsberg J, Strieth S, Dietrich D. Hoffmann F, et al. Among authors: zarbl r. Clin Epigenetics. 2023 Jul 6;15(1):112. doi: 10.1186/s13148-023-01525-6. Clin Epigenetics. 2023. PMID: 37415208 Free PMC article.
DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients' survival, immune cell infiltrates, mutational load, and interferon γ signature.
Sailer V, Sailer U, Bawden EG, Zarbl R, Wiek C, Vogt TJ, Dietrich J, Loick S, Grünwald I, Toma M, Golletz C, Gerstner A, Kristiansen G, Bootz F, Scheckenbach K, Landsberg J, Dietrich D. Sailer V, et al. Among authors: zarbl r. EBioMedicine. 2019 Oct;48:341-352. doi: 10.1016/j.ebiom.2019.09.038. Epub 2019 Oct 15. EBioMedicine. 2019. PMID: 31628024 Free PMC article.
Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma.
Hoffmann F, Zarbl R, Niebel D, Sirokay J, Fröhlich A, Posch C, Holderried TAW, Brossart P, Saavedra G, Kuster P, Strieth S, Gielen GH, Ring SS, Dietrich J, Pietsch T, Flatz L, Kristiansen G, Landsberg J, Dietrich D. Hoffmann F, et al. Among authors: zarbl r. Clin Epigenetics. 2020 Jun 26;12(1):94. doi: 10.1186/s13148-020-00883-9. Clin Epigenetics. 2020. PMID: 32586358 Free PMC article.
CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab).
Fietz S, Zarbl R, Niebel D, Posch C, Brossart P, Gielen GH, Strieth S, Pietsch T, Kristiansen G, Bootz F, Landsberg J, Dietrich D. Fietz S, et al. Among authors: zarbl r. Cancer Immunol Immunother. 2021 Jun;70(6):1781-1788. doi: 10.1007/s00262-020-02777-4. Epub 2020 Nov 16. Cancer Immunol Immunother. 2021. PMID: 33196890 Free PMC article.
Fibroblast growth factor (FGF), FGF receptor (FGFR), and cyclin D1 (CCND1) DNA methylation in head and neck squamous cell carcinomas is associated with transcriptional activity, gene amplification, human papillomavirus (HPV) status, and sensitivity to tyrosine kinase inhibitors.
Bao Y, Gabrielpillai J, Dietrich J, Zarbl R, Strieth S, Schröck F, Dietrich D. Bao Y, et al. Among authors: zarbl r. Clin Epigenetics. 2021 Dec 21;13(1):228. doi: 10.1186/s13148-021-01212-4. Clin Epigenetics. 2021. PMID: 34933671 Free PMC article.
DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy.
Niebel D, Fröhlich A, Zarbl R, Fietz S, de Vos L, Vogt TJ, Dietrich J, Sirokay J, Kuster P, Saavedra G, Ramírez Valladolid S, Hoffmann F, Strieth S, Landsberg J, Dietrich D. Niebel D, et al. Among authors: zarbl r. Clin Epigenetics. 2022 Apr 11;14(1):50. doi: 10.1186/s13148-022-01270-2. Clin Epigenetics. 2022. PMID: 35410311 Free PMC article.
CTLA4 , PD-1 , PD-L1 , PD-L2 , TIM-3 , TIGIT , and LAG3 DNA Methylation Is Associated With BAP1 -Aberrancy, Transcriptional Activity, and Overall Survival in Uveal Melanoma.
de Vos L, Carrillo Cano TM, Zarbl R, Klümper N, Ralser DJ, Franzen A, Herr E, Gabrielpillai J, Vogt TJ, Dietrich J, Strieth S, Landsberg J, Dietrich D. de Vos L, et al. Among authors: zarbl r. J Immunother. 2022 Sep 1;45(7):324-334. doi: 10.1097/CJI.0000000000000429. Epub 2022 Jul 22. J Immunother. 2022. PMID: 35862127
ICOS DNA methylation regulates melanoma cell-intrinsic ICOS expression, is associated with melanoma differentiation, prognosis, and predicts response to immune checkpoint blockade.
Ralser DJ, Herr E, de Vos L, Kulcsár Z, Zarbl R, Klümper N, Gielen GH, Maas AP, Hoffmann F, Dietrich J, Kuster P, Mustea A, Glodde N, Kristiansen G, Strieth S, Landsberg J, Dietrich D. Ralser DJ, et al. Among authors: zarbl r. Biomark Res. 2023 Jun 1;11(1):56. doi: 10.1186/s40364-023-00508-2. Biomark Res. 2023. PMID: 37259155 Free PMC article.
22 results