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Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression.
Zemanová N, Lněničková K, Vavrečková M, Anzenbacherová E, Anzenbacher P, Zapletalová I, Hermanová P, Hudcovic T, Kozáková H, Jourová L. Zemanová N, et al. Among authors: zapletalova i. PLoS One. 2021 Nov 9;16(11):e0259643. doi: 10.1371/journal.pone.0259643. eCollection 2021. PLoS One. 2021. PMID: 34752478 Free PMC article.
In vivo evaluation of effect of anthocyanin-rich wheat on rat liver microsomal drug-metabolizing cytochromes P450 and on biochemical and antioxidant parameters in rats.
Prokop J, Anzenbacher P, Mrkvicová E, Pavlata L, Zapletalová I, Šťastník O, Martinek P, Kosina P, Anzenbacherová E. Prokop J, et al. Among authors: zapletalova i. Food Chem Toxicol. 2018 Dec;122:225-233. doi: 10.1016/j.fct.2018.10.029. Epub 2018 Oct 11. Food Chem Toxicol. 2018. PMID: 30316842
Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats.
Prokop J, Lněničková K, Cibiček N, Kosina P, Tománková V, Jourová L, Láníčková T, Skálová L, Szotáková B, Anzenbacher P, Zapletalová I, Rácová Z, Anzenbacherová E, Ulrichová J. Prokop J, et al. Among authors: zapletalova i. Food Chem Toxicol. 2019 Jul;129:382-390. doi: 10.1016/j.fct.2019.04.051. Epub 2019 May 3. Food Chem Toxicol. 2019. PMID: 31059744
In vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450.
Špičáková A, Kraus P, Gucký T, Kryštof V, Strnad M, Bazgier V, Otyepka M, Kubíčková V, Poruba M, Rácová Z, Zapletalová I, Anzenbacher P. Špičáková A, et al. Among authors: zapletalova i. Physiol Res. 2020 Dec 31;69(Suppl 4):S627-S636. doi: 10.33549/physiolres.934611. Physiol Res. 2020. PMID: 33646005 Free PMC article.
Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice.
Grycová A, Joo H, Maier V, Illés P, Vyhlídalová B, Poulíková K, Sládeková L, Nádvorník P, Vrzal R, Zemánková L, Pečinková P, Poruba M, Zapletalová I, Večeřa R, Anzenbacher P, Ehrmann J, Ondra P, Jung JW, Mani S, Dvořák Z. Grycová A, et al. Among authors: zapletalova i. J Med Chem. 2022 May 12;65(9):6859-6868. doi: 10.1021/acs.jmedchem.2c00208. Epub 2022 Apr 13. J Med Chem. 2022. PMID: 35416668
15 results