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PIN1 in breast development and cancer: a clinical perspective.
Rustighi A, Zannini A, Campaner E, Ciani Y, Piazza S, Del Sal G. Rustighi A, et al. Among authors: zannini a. Cell Death Differ. 2017 Feb;24(2):200-211. doi: 10.1038/cdd.2016.122. Epub 2016 Nov 11. Cell Death Differ. 2017. PMID: 27834957 Free PMC article. Review.
Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.
Rustighi A, Zannini A, Tiberi L, Sommaggio R, Piazza S, Sorrentino G, Nuzzo S, Tuscano A, Eterno V, Benvenuti F, Santarpia L, Aifantis I, Rosato A, Bicciato S, Zambelli A, Del Sal G. Rustighi A, et al. Among authors: zannini a. EMBO Mol Med. 2014 Jan;6(1):99-119. doi: 10.1002/emmm.201302909. Epub 2013 Dec 15. EMBO Mol Med. 2014. PMID: 24357640 Free PMC article.
Glucocorticoid receptor signalling activates YAP in breast cancer.
Sorrentino G, Ruggeri N, Zannini A, Ingallina E, Bertolio R, Marotta C, Neri C, Cappuzzello E, Forcato M, Rosato A, Mano M, Bicciato S, Del Sal G. Sorrentino G, et al. Among authors: zannini a. Nat Commun. 2017 Jan 19;8:14073. doi: 10.1038/ncomms14073. Nat Commun. 2017. PMID: 28102225 Free PMC article.
A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.
Campaner E, Rustighi A, Zannini A, Cristiani A, Piazza S, Ciani Y, Kalid O, Golan G, Baloglu E, Shacham S, Valsasina B, Cucchi U, Pippione AC, Lolli ML, Giabbai B, Storici P, Carloni P, Rossetti G, Benvenuti F, Bello E, D'Incalci M, Cappuzzello E, Rosato A, Del Sal G. Campaner E, et al. Among authors: zannini a. Nat Commun. 2017 Jun 9;8:15772. doi: 10.1038/ncomms15772. Nat Commun. 2017. PMID: 28598431 Free PMC article.
Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis.
Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, Severino LU, Scaini D, Mano M, Mantovani F, Rosato A, Bicciato S, Piccolo S, Del Sal G. Ingallina E, et al. Among authors: zannini a. Nat Cell Biol. 2018 Jan;20(1):28-35. doi: 10.1038/s41556-017-0009-8. Epub 2017 Dec 18. Nat Cell Biol. 2018. PMID: 29255172 Free PMC article.
Oncogenic Hijacking of the PIN1 Signaling Network.
Zannini A, Rustighi A, Campaner E, Del Sal G. Zannini A, et al. Front Oncol. 2019 Feb 25;9:94. doi: 10.3389/fonc.2019.00094. eCollection 2019. Front Oncol. 2019. PMID: 30873382 Free PMC article. Review.
Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment.
Campaner E, Zannini A, Santorsola M, Bonazza D, Bottin C, Cancila V, Tripodo C, Bortul M, Zanconati F, Schoeftner S, Del Sal G. Campaner E, et al. Among authors: zannini a. Cancers (Basel). 2020 Dec 21;12(12):3869. doi: 10.3390/cancers12123869. Cancers (Basel). 2020. PMID: 33371412 Free PMC article.
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