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Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double-Blind, Randomized, Placebo-Controlled Phase 1 Clinical Study.
Hunt H, Donaldson K, Strem M, Zann V, Leung P, Sweet S, Connor A, Combs D, Belanoff J. Hunt H, et al. Among authors: zann v. Clin Pharmacol Drug Dev. 2018 May;7(4):408-421. doi: 10.1002/cpdd.389. Epub 2017 Oct 2. Clin Pharmacol Drug Dev. 2018. PMID: 28967708 Free PMC article. Clinical Trial.
Safety, Pharmacokinetics, and Pharmacodynamics of ME-401, an Oral, Potent, and Selective Inhibitor of Phosphatidylinositol 3-Kinase P110δ, Following Single Ascending Dose Administration to Healthy Volunteers.
Moreno O, Butler T, Zann V, Willson A, Leung P, Connor A. Moreno O, et al. Among authors: zann v. Clin Ther. 2018 Nov;40(11):1855-1867. doi: 10.1016/j.clinthera.2018.09.006. Epub 2018 Oct 26. Clin Ther. 2018. PMID: 30458930 Free article. Clinical Trial.
Novel formulation of abiraterone acetate might allow significant dose reduction and eliminates substantial positive food effect.
Solymosi T, Ötvös Z, Angi R, Ordasi B, Jordán T, Molnár L, McDermott J, Zann V, Church A, Mair S, Filipcsei G, Heltovics G, Glavinas H. Solymosi T, et al. Among authors: zann v. Cancer Chemother Pharmacol. 2017 Oct;80(4):723-728. doi: 10.1007/s00280-017-3406-6. Epub 2017 Aug 3. Cancer Chemother Pharmacol. 2017. PMID: 28776077 Clinical Trial.
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