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Role of YAP/TAZ in mechanotransduction.
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, Elvassore N, Piccolo S. Dupont S, et al. Among authors: zanconato f. Nature. 2011 Jun 8;474(7350):179-83. doi: 10.1038/nature10137. Nature. 2011. PMID: 21654799
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells.
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S. Cordenonsi M, et al. Among authors: zanconato f. Cell. 2011 Nov 11;147(4):759-72. doi: 10.1016/j.cell.2011.09.048. Cell. 2011. PMID: 22078877 Free article.
Role of TAZ as mediator of Wnt signaling.
Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S. Azzolin L, et al. Among authors: zanconato f. Cell. 2012 Dec 21;151(7):1443-56. doi: 10.1016/j.cell.2012.11.027. Epub 2012 Dec 13. Cell. 2012. PMID: 23245942 Free article.
YAP/TAZ as therapeutic targets in cancer.
Zanconato F, Battilana G, Cordenonsi M, Piccolo S. Zanconato F, et al. Curr Opin Pharmacol. 2016 Aug;29:26-33. doi: 10.1016/j.coph.2016.05.002. Epub 2016 Jun 2. Curr Opin Pharmacol. 2016. PMID: 27262779 Free PMC article. Review.
YAP/TAZ at the Roots of Cancer.
Zanconato F, Cordenonsi M, Piccolo S. Zanconato F, et al. Cancer Cell. 2016 Jun 13;29(6):783-803. doi: 10.1016/j.ccell.2016.05.005. Cancer Cell. 2016. PMID: 27300434 Free PMC article. Review.
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4.
Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S. Zanconato F, et al. Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17. Nat Med. 2018. PMID: 30224758 Free PMC article.
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S. Chang L, et al. Among authors: zanconato f. Nature. 2018 Nov;563(7730):265-269. doi: 10.1038/s41586-018-0658-1. Epub 2018 Oct 31. Nature. 2018. PMID: 30401838 Free PMC article.
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