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In vaccinated individuals serum bactericidal activity against B meningococci is abrogated by C5 inhibition but not by inhibition of the alternative complement pathway.
Ispasanie E, Muri L, Schmid M, Schubart A, Thorburn C, Zamurovic N, Holbro T, Kammüller M, Pluschke G. Ispasanie E, et al. Among authors: zamurovic n. Front Immunol. 2023 Jun 29;14:1180833. doi: 10.3389/fimmu.2023.1180833. eCollection 2023. Front Immunol. 2023. PMID: 37457736 Free PMC article.
Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.
Martin K, Touil R, Kolb Y, Cvijetic G, Murakami K, Israel L, Duraes F, Buffet D, Glück A, Niwa S, Bigaud M, Junt T, Zamurovic N, Smith P, McCoy KD, Ohashi PS, Bornancin F, Calzascia T. Martin K, et al. Among authors: zamurovic n. J Immunol. 2019 Dec 1;203(11):2791-2806. doi: 10.4049/jimmunol.1900327. Epub 2019 Oct 28. J Immunol. 2019. PMID: 31659015 Free PMC article.
Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.
Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, Weckbecker G, Zenke G, Kinzel B, Traggiai E, Brenner D, Brüstle A, St Paul M, Zamurovic N, McCoy KD, Rolink A, Régnier CH, Mak TW, Ohashi PS, Patel DD, Calzascia T. Bornancin F, et al. Among authors: zamurovic n. J Immunol. 2015 Apr 15;194(8):3723-34. doi: 10.4049/jimmunol.1402254. Epub 2015 Mar 11. J Immunol. 2015. PMID: 25762782
LTA4H inhibitor LYS006: Clinical PK/PD and safety in a randomized phase I clinical trial.
Loesche C, Picard D, Van Hoorick B, Schuhmann I, Jäger P, Klein K, Schuhler C, Thoma G, Markert C, Poller B, Zamurovic N, Weiss HM, Otto H, Fink M, Röhn TA. Loesche C, et al. Among authors: zamurovic n. Clin Transl Sci. 2024 Feb;17(2):e13724. doi: 10.1111/cts.13724. Clin Transl Sci. 2024. PMID: 38407540 Free PMC article. Clinical Trial.
Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice.
Shimshek DR, Jacobson LH, Kolly C, Zamurovic N, Balavenkatraman KK, Morawiec L, Kreutzer R, Schelle J, Jucker M, Bertschi B, Theil D, Heier A, Bigot K, Beltz K, Machauer R, Brzak I, Perrot L, Neumann U. Shimshek DR, et al. Among authors: zamurovic n. Sci Rep. 2016 Feb 25;6:21917. doi: 10.1038/srep21917. Sci Rep. 2016. PMID: 26912421 Free PMC article.
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