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KAP1 is a new non-genetic vulnerability of malignant pleural mesothelioma (MPM).
Lorenzini E, Torricelli F, Zamponi R, Donati B, Manicardi V, Sauta E, Faria do Valle I, Reggiani F, Gugnoni M, Manzotti G, Fragliasso V, Vitale E, Piana S, Sancisi V, Ciarrocchi A. Lorenzini E, et al. Among authors: zamponi r. NAR Cancer. 2022 Jul 29;4(3):zcac024. doi: 10.1093/narcan/zcac024. eCollection 2022 Sep. NAR Cancer. 2022. PMID: 35910692 Free PMC article.
Acute Radiation Colitis after Preoperative Short-Course Radiotherapy for Rectal Cancer: A Morphological, Immunohistochemical and Genetic Study.
Zanelli M, Ciarrocchi A, De Petris G, Zizzo M, Costantini M, Bisagni A, Torricelli F, Nicoli D, Ramundo D, Ricci S, Palicelli A, Sanguedolce F, Ascani S, Castro Ruiz C, Annessi V, Zamponi R, Bortesi M, Martino V, Marchetti M, De Marco L. Zanelli M, et al. Among authors: zamponi r. Cancers (Basel). 2020 Sep 9;12(9):2571. doi: 10.3390/cancers12092571. Cancers (Basel). 2020. PMID: 32917028 Free PMC article.
USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.
Ji L, Lu B, Zamponi R, Charlat O, Aversa R, Yang Z, Sigoillot F, Zhu X, Hu T, Reece-Hoyes JS, Russ C, Michaud G, Tchorz JS, Jiang X, Cong F. Ji L, et al. Among authors: zamponi r. Nat Commun. 2019 Sep 13;10(1):4184. doi: 10.1038/s41467-019-12143-3. Nat Commun. 2019. PMID: 31519875 Free PMC article.
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.
Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. Hao HX, et al. Among authors: zamponi r. Nature. 2012 Apr 29;485(7397):195-200. doi: 10.1038/nature11019. Nature. 2012. PMID: 22575959
mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level.
Zeng H, Lu B, Zamponi R, Yang Z, Wetzel K, Loureiro J, Mohammadi S, Beibel M, Bergling S, Reece-Hoyes J, Russ C, Roma G, Tchorz JS, Capodieci P, Cong F. Zeng H, et al. Among authors: zamponi r. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10362-E10369. doi: 10.1073/pnas.1808575115. Epub 2018 Oct 8. Proc Natl Acad Sci U S A. 2018. PMID: 30297426 Free PMC article.
Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites.
Paul A, Annunziato S, Lu B, Sun T, Evrova O, Planas-Paz L, Orsini V, Terracciano LM, Charlat O, Loureiro ZY, Ji L, Zamponi R, Sigoillot F, Lei H, Lindeman A, Russ C, Reece-Hoyes JS, Nicholson TB, Tchorz JS, Cong F. Paul A, et al. Among authors: zamponi r. Nat Commun. 2022 Feb 17;13(1):930. doi: 10.1038/s41467-022-28567-3. Nat Commun. 2022. PMID: 35177623 Free PMC article.
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