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Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation.
Silva CMS, Wanderley CWS, Veras FP, Sonego F, Nascimento DC, Gonçalves AV, Martins TV, Cólon DF, Borges VF, Brauer VS, Damasceno LEA, Silva KP, Toller-Kawahisa JE, Batah SS, Souza ALJ, Monteiro VS, Oliveira AER, Donate PB, Zoppi D, Borges MC, Almeida F, Nakaya HI, Fabro AT, Cunha TM, Alves-Filho JC, Zamboni DS, Cunha FQ. Silva CMS, et al. Among authors: zamboni ds. Blood. 2021 Dec 23;138(25):2702-2713. doi: 10.1182/blood.2021011525. Blood. 2021. PMID: 34407544 Free PMC article.
MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.
Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ. Sônego F, et al. Among authors: zamboni ds. PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014. PLoS One. 2014. PMID: 25084278 Free PMC article.
NOD2 contributes to Porphyromonas gingivalis-induced bone resorption.
Prates TP, Taira TM, Holanda MC, Bignardi LA, Salvador SL, Zamboni DS, Cunha FQ, Fukada SY. Prates TP, et al. Among authors: zamboni ds. J Dent Res. 2014 Nov;93(11):1155-62. doi: 10.1177/0022034514551770. Epub 2014 Sep 19. J Dent Res. 2014. PMID: 25239844 Free PMC article.
NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis.
Nascimento MS, Ferreira MD, Quirino GF, Maruyama SR, Krishnaswamy JK, Liu D, Berlink J, Fonseca DM, Zamboni DS, Carregaro V, Almeida RP, Cunha TM, Eisenbarth SS, Silva JS. Nascimento MS, et al. Among authors: zamboni ds. J Infect Dis. 2016 Dec 1;214(11):1647-1657. doi: 10.1093/infdis/jiw446. Epub 2016 Sep 20. J Infect Dis. 2016. PMID: 27651416
152 results