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Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Among authors: zalmas lp. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer.
Kanu N, Cerone MA, Goh G, Zalmas LP, Bartkova J, Dietzen M, McGranahan N, Rogers R, Law EK, Gromova I, Kschischo M, Walton MI, Rossanese OW, Bartek J, Harris RS, Venkatesan S, Swanton C. Kanu N, et al. Among authors: zalmas lp. Genome Biol. 2016 Sep 15;17(1):185. doi: 10.1186/s13059-016-1042-9. Genome Biol. 2016. PMID: 27634334 Free PMC article.
Cyclin D mediates tolerance of genome-doubling in cancers with functional p53.
Crockford A, Zalmas LP, Grönroos E, Dewhurst SM, McGranahan N, Cuomo ME, Encheva V, Snijders AP, Begum J, Purewal S, Cerveira J, Patel H, Renshaw MJ, Swanton C. Crockford A, et al. Among authors: zalmas lp. Ann Oncol. 2017 Jan 1;28(1):149-156. doi: 10.1093/annonc/mdw612. Ann Oncol. 2017. PMID: 28177473 Free PMC article.
The PROTACtable genome.
Schneider M, Radoux CJ, Hercules A, Ochoa D, Dunham I, Zalmas LP, Hessler G, Ruf S, Shanmugasundaram V, Hann MM, Thomas PJ, Queisser MA, Benowitz AB, Brown K, Leach AR. Schneider M, et al. Among authors: zalmas lp. Nat Rev Drug Discov. 2021 Oct;20(10):789-797. doi: 10.1038/s41573-021-00245-x. Epub 2021 Jul 20. Nat Rev Drug Discov. 2021. PMID: 34285415 Review.
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1.
Zheng S, Moehlenbrink J, Lu YC, Zalmas LP, Sagum CA, Carr S, McGouran JF, Alexander L, Fedorov O, Munro S, Kessler B, Bedford MT, Yu Q, La Thangue NB. Zheng S, et al. Among authors: zalmas lp. Mol Cell. 2013 Oct 10;52(1):37-51. doi: 10.1016/j.molcel.2013.08.039. Epub 2013 Sep 26. Mol Cell. 2013. PMID: 24076217 Free PMC article.
Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor.
Carr SM, Munro S, Zalmas LP, Fedorov O, Johansson C, Krojer T, Sagum CA, Bedford MT, Oppermann U, La Thangue NB. Carr SM, et al. Among authors: zalmas lp. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11341-6. doi: 10.1073/pnas.1403737111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049398 Free PMC article.
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