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Comprehensive study of the drug delivery properties of poly(l-lactide)-poly(ethylene glycol) nanoparticles in rats and tumor-bearing mice.
Shalgunov V, Zaytseva-Zotova D, Zintchenko A, Levada T, Shilov Y, Andreyev D, Dzhumashev D, Metelkin E, Urusova A, Demin O, McDonnell K, Troiano G, Zale S, Safarovа E. Shalgunov V, et al. Among authors: zale s. J Control Release. 2017 Sep 10;261:31-42. doi: 10.1016/j.jconrel.2017.06.006. Epub 2017 Jun 10. J Control Release. 2017. PMID: 28611009 Free article.
Nanomedicines: From Bench to Bedside and Beyond.
Havel H, Finch G, Strode P, Wolfgang M, Zale S, Bobe I, Youssoufian H, Peterson M, Liu M. Havel H, et al. Among authors: zale s. AAPS J. 2016 Nov;18(6):1373-1378. doi: 10.1208/s12248-016-9961-7. Epub 2016 Aug 1. AAPS J. 2016. PMID: 27480318 Review.
Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo.
Ashton S, Song YH, Nolan J, Cadogan E, Murray J, Odedra R, Foster J, Hall PA, Low S, Taylor P, Ellston R, Polanska UM, Wilson J, Howes C, Smith A, Goodwin RJ, Swales JG, Strittmatter N, Takáts Z, Nilsson A, Andren P, Trueman D, Walker M, Reimer CL, Troiano G, Parsons D, De Witt D, Ashford M, Hrkach J, Zale S, Jewsbury PJ, Barry ST. Ashton S, et al. Among authors: zale s. Sci Transl Med. 2016 Feb 10;8(325):325ra17. doi: 10.1126/scitranslmed.aad2355. Sci Transl Med. 2016. PMID: 26865565 Free article.
Phase I Study of PSMA-Targeted Docetaxel-Containing Nanoparticle BIND-014 in Patients with Advanced Solid Tumors.
Von Hoff DD, Mita MM, Ramanathan RK, Weiss GJ, Mita AC, LoRusso PM, Burris HA 3rd, Hart LL, Low SC, Parsons DM, Zale SE, Summa JM, Youssoufian H, Sachdev JC. Von Hoff DD, et al. Among authors: zale se. Clin Cancer Res. 2016 Jul 1;22(13):3157-63. doi: 10.1158/1078-0432.CCR-15-2548. Epub 2016 Feb 4. Clin Cancer Res. 2016. PMID: 26847057 Clinical Trial.
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile.
Hrkach J, Von Hoff D, Mukkaram Ali M, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, Low S, McDonnell K, Peeke E, Retnarajan B, Sabnis A, Schnipper E, Song JJ, Song YH, Summa J, Tompsett D, Troiano G, Van Geen Hoven T, Wright J, LoRusso P, Kantoff PW, Bander NH, Sweeney C, Farokhzad OC, Langer R, Zale S. Hrkach J, et al. Among authors: zale s. Sci Transl Med. 2012 Apr 4;4(128):128ra39. doi: 10.1126/scitranslmed.3003651. Sci Transl Med. 2012. PMID: 22491949
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