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Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression.
Zakraoui O, Marcinkiewicz C, Aloui Z, Othman H, Grépin R, Haoues M, Essafi M, Srairi-Abid N, Gasmi A, Karoui H, Pagès G, Essafi-Benkhadir K. Zakraoui O, et al. Mol Carcinog. 2017 Jan;56(1):18-35. doi: 10.1002/mc.22470. Epub 2016 Jan 29. Mol Carcinog. 2017. PMID: 26824338
Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells.
Hammouda MB, Montenegro MF, Sánchez-Del-Campo L, Zakraoui O, Aloui Z, Riahi-Chebbi I, Karoui H, Rodríguez-López JN, Essafi-Benkhadir K. Hammouda MB, et al. Among authors: zakraoui o. Toxins (Basel). 2016 Jul 5;8(7):206. doi: 10.3390/toxins8070206. Toxins (Basel). 2016. PMID: 27399772 Free PMC article.
Mertensene, a Halogenated Monoterpene, Induces G2/M Cell Cycle Arrest and Caspase Dependent Apoptosis of Human Colon Adenocarcinoma HT29 Cell Line through the Modulation of ERK-1/-2, AKT and NF-κB Signaling.
Tarhouni-Jabberi S, Zakraoui O, Ioannou E, Riahi-Chebbi I, Haoues M, Roussis V, Kharrat R, Essafi-Benkhadir K. Tarhouni-Jabberi S, et al. Among authors: zakraoui o. Mar Drugs. 2017 Jul 20;15(7):221. doi: 10.3390/md15070221. Mar Drugs. 2017. PMID: 28726723 Free PMC article.
Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A.
Harigua-Souiai E, Abdelkrim YZ, Bassoumi-Jamoussi I, Zakraoui O, Bouvier G, Essafi-Benkhadir K, Banroques J, Desdouits N, Munier-Lehmann H, Barhoumi M, Tanner NK, Nilges M, Blondel A, Guizani I. Harigua-Souiai E, et al. Among authors: zakraoui o. PLoS Negl Trop Dis. 2018 Jan 18;12(1):e0006160. doi: 10.1371/journal.pntd.0006160. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29346371 Free PMC article.
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
Kasap C, Izgutdina A, Patiño-Escobar B, Kang A, Chilakapati N, Akagi N, Johnson H, Rashid T, Werner J, Barpanda A, Geng H, Lin YT, Rampersaud S, Gil-Alós D, Sobh A, Dupéré-Richer D, Wicaksono G, Kawehi Kelii KM, Dalal R, Ramos E, Vijayanarayanan A, Salangsang F, Phojanakong P, Serrano JAC, Zakraoui O, Tariq I, Steri V, Shanmugam M, Boise LH, Kortemme T, Stieglitz E, Licht JD, Karlon WJ, Barwick BG, Wiita AP. Kasap C, et al. Among authors: zakraoui o. bioRxiv [Preprint]. 2024 Feb 28:2024.02.24.581875. doi: 10.1101/2024.02.24.581875. bioRxiv. 2024. PMID: 38463958 Free PMC article. Preprint.