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The Lipophilic Purine Nucleoside-Tdp1 Inhibitor-Enhances DNA Damage Induced by Topotecan In Vitro and Potentiates the Antitumor Effect of Topotecan In Vivo.
Chernyshova IA, Zakharenko AL, Kurochkin NN, Dyrkheeva NS, Kornienko TE, Popova NA, Nikolin VP, Ilina ES, Zharkov TD, Kupryushkin MS, Oslovsky VE, Drenichev MS, Lavrik OI. Chernyshova IA, et al. Among authors: zakharenko al. Molecules. 2022 Dec 31;28(1):323. doi: 10.3390/molecules28010323. Molecules. 2022. PMID: 36615517 Free PMC article.
Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor.
Dyrkheeva NS, Malakhova AA, Zakharenko AL, Okorokova LS, Shtokalo DN, Pavlova SV, Medvedev SP, Zakian SM, Nushtaeva AA, Tupikin AE, Kabilov MR, Khodyreva SN, Luzina OA, Salakhutdinov NF, Lavrik OI. Dyrkheeva NS, et al. Among authors: zakharenko al. Int J Mol Sci. 2023 Mar 7;24(6):5148. doi: 10.3390/ijms24065148. Int J Mol Sci. 2023. PMID: 36982223 Free PMC article.
Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockout.
Dyrkheeva NS, Zakharenko AL, Malakhova AA, Okorokova LS, Shtokalo DN, Medvedev SP, Tupikin AA, Kabilov MR, Lavrik OI. Dyrkheeva NS, et al. Among authors: zakharenko al. Biochim Biophys Acta Gen Subj. 2024 Apr 14;1868(7):130616. doi: 10.1016/j.bbagen.2024.130616. Online ahead of print. Biochim Biophys Acta Gen Subj. 2024. PMID: 38621596
Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice with Lewis Carcinoma by Tdp1 Inhibitors-New Usnic Acid Derivatives.
Kornienko TE, Chepanova AA, Zakharenko AL, Filimonov AS, Luzina OA, Dyrkheeva NS, Nikolin VP, Popova NA, Salakhutdinov NF, Lavrik OI. Kornienko TE, et al. Among authors: zakharenko al. Int J Mol Sci. 2024 Jan 19;25(2):1210. doi: 10.3390/ijms25021210. Int J Mol Sci. 2024. PMID: 38279210 Free PMC article.
Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan.
Okhina AA, Kornienko TE, Rogachev AD, Luzina OA, Popova NA, Nikolin VP, Zakharenko AL, Dyrkheeva NS, Pokrovsky AG, Salakhutdinov NF, Lavrik OI. Okhina AA, et al. Among authors: zakharenko al. J Pharm Biomed Anal. 2023 Nov 30;236:115731. doi: 10.1016/j.jpba.2023.115731. Epub 2023 Sep 18. J Pharm Biomed Anal. 2023. PMID: 37741072
[Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo].
Kornienko TE, Zakharenko AL, Ilina ES, Chepanova AA, Zakharova OD, Dyrkheeva NS, Popova NA, Nikolin VP, Filimonov AS, Luzina OA, Salakhutdinov NF, Lavrik OI. Kornienko TE, et al. Among authors: zakharenko al. Mol Biol (Mosk). 2023 Mar-Apr;57(2):220-231. Mol Biol (Mosk). 2023. PMID: 37000651 Russian.
51 results